{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T01:31:38Z","timestamp":1778635898339,"version":"3.51.4"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T00:00:00Z","timestamp":1567987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["2016\u2010ER6304\u201002"],"award-info":[{"award-number":["2016\u2010ER6304\u201002"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hypertension and diabetes mellitus (DM) are major risk factors for the cardiovascular disease. In this retrospective cohort study, we compared the long\u2010term clinical outcomes between antecedent hypertension and DM in acute myocardial infarction (AMI) patients after stent implantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 32\u2009938 eligible AMI patients were enrolled and divided into the four groups according to the presence or absence of hypertension and DM (hypertension \u2212\/DM \u2212[group A, 13\u2009773 patients], hypertension +\/DM \u2212[group B, 10\u2009395 patients], hypertension \u2212\/DM + [group C, 3050 patients], and hypertension +\/DM + [group D, 5720 patients]). The clinical endpoint was the cumulative incidence of major adverse cardiac events (MACEs) defined as all\u2010cause death, recurrent myocardial infarction (Re\u2010MI) and any repeat revascularization during the 2\u2010year follow\u2010up period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After adjustment, the cumulative incidence of MACEs (adjusted hazard ratio [aHR], 1.232; 95% confidence interval [CI], 0.982\u20101.567; <jats:italic>P<\/jats:italic> =\u2009.071), all\u2010cause death, and e\u2010MI Re\u2010MI were similar between the group B and C. However, the cumulative incidences of any repeat revascularization (aHR, 1.438; 95% CI, 1.062\u20101.997; <jats:italic>P<\/jats:italic> = .007), target lesion revascularization (TLR) (aHR, 2.467; 95% CI, 1.552\u20103.922; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), and target vessel revascularization (TVR) (aHR, 1.671; 95% CI, 1.256\u20102.222; <jats:italic>P<\/jats:italic> &lt;\u2009.001) were significantly higher in group C compared with group B.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This large number of a nonrandomized and multicenter cohort study clearly demonstrated the detrimental impacts of the hypertension and diabetes on long\u2010term clinical outcomes. Moreover, higher incidence of repeat revascularization after PCI in diabetic AMI patients a major concern until recently.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1753-0407.12979","type":"journal-article","created":{"date-parts":[[2019,8,17]],"date-time":"2019-08-17T07:44:34Z","timestamp":1566027874000},"page":"119-133","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Which is the worst risk factor for the long\u2010term clinical outcome? Comparison of long\u2010term clinical outcomes between antecedent hypertension and diabetes mellitus in South Korean acute myocardial infarction patients after stent implantation"],"prefix":"10.1111","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9669-3598","authenticated-orcid":false,"given":"Yong Hoon","family":"Kim","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine Kangwon National University School of Medicine  Chuncheon South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ae\u2010Young","family":"Her","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine Kangwon National University School of Medicine  Chuncheon South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung Ho","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Cardiology Chonnam National University Hospital  Gwangju South 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