{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:33:21Z","timestamp":1791891201466,"version":"4.3.4"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,11,24]],"date-time":"2019-11-24T00:00:00Z","timestamp":1574553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Male obesity is suggested to impact negatively on male fertility and semen quality in numerous studies. However, previous literatures regarding health effects of the metabolic syndrome (MetS) on semen quality are rare and inconsistent. The aim of this study is to investigate the relationship between MetS and sperm parameters in a Taiwanese reproductive\u2010age male population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 8395 men who attended a private medical screening program in Taiwan from 2010 to 2016 were included in this cross\u2010sectional study. Semen analysis was assessed in accordance with the WHO guidelines and included sperm concentration, total motility, progressive motility, and morphology. MetS was defined by the modified National Cholesterol Education Program Third Adult Treatment Panel (NCEP ATP III) criteria with the Asian cutoff for waist circumference (WC). The associations between MetS and semen analysis were examined by multivariable linear regressions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After fully adjusting for pertinent covariables, MetS was significantly associated with a reduced percentage of sperm normal morphology. Blood pressure, WC, and serum glucose had a significantly negative association with sperm normal morphology. Individuals with an increased number of MetS components had a closer association with reduced sperm progressive motility and the percentage of normal morphology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MetS and its components exhibited deleterious effects on semen quality among reproductive\u2010age men. Further studies are warranted to explore these pathophysiologic relationship and underlying mechanisms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1753-0407.12995","type":"journal-article","created":{"date-parts":[[2019,10,12]],"date-time":"2019-10-12T13:58:57Z","timestamp":1570888737000},"page":"294-304","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Metabolic syndrome and semen quality in adult population"],"prefix":"10.1111","volume":"12","author":[{"given":"Yuan\u2010Yuei","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Tri\u2010Service General Hospital Songshan Branch; and School of Medicine National Defense Medical Center  Taipei Republic of China"},{"name":"Division of Family Medicine, Department of Family and Community Medicine, Tri\u2010Service General Hospital; and School of Medicine National Defense Medical Center  Taipei Republic of China"},{"name":"Department 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