{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:05:51Z","timestamp":1791497151789,"version":"4.3.4"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T00:00:00Z","timestamp":1606694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008977","name":"Universit\u00e4t Ulm","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008977","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Children with type 1 diabetes (T1D) are at much higher risk of developing celiac disease (CD) than the general population. The aim of the study was to assess the prevalence and differences in clinical presentation of CD in T1D in different regions of the world.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study is based on the Better control in Pediatric and Adolescent diabete<jats:bold>S<\/jats:bold>: <jats:bold>W<\/jats:bold>orking to cr<jats:bold>E<\/jats:bold>ate c<jats:bold>E<\/jats:bold>n<jats:bold>T<\/jats:bold>ers of Reference (SWEET) database. There were 57\u2009375 patients included in the study, aged \u226418\u2009years from 54 SWEET centers. Only centers with screening for celiac disease were included. Regression models adjusted for age, diabetes duration, and gender and a fixed effect in the models for region was used. Diabetes duration, age at diabetes onset, and sex were presented as unadjusted results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CD was present in 2652 subjects (4.5%), with different prevalence among regions: from 1.9% in Asia\/Middle East to 6.9% in Australia\/New Zealand. CD was observed more often among females. Comparing children with and without CD, characteristics for those with CD were younger age at diabetes onset (6.3 [3.3; 9.8] vs 8.1 [4.6; 11.3], <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and had longer diabetes duration (6.4 [3.6; 9.8] vs 4.8 [2.1; 8.2], <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Further, they had lower glycosylated hemoglobin (HbA1c) in Europe and North America\/Canada; lower body mass index (BMI)\u2010SD score (BMI\u2010SDS) in southern Europe, North America, and Canada; In most regions daily insulin dose was lower, height\u2010SDS was lower, and the percentage of insulin pump users was higher in children with T1D and CD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The prevalence and the anthropometric and metabolic consequences of CD in children with T1D differ around the world.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1753-0407.13126","type":"journal-article","created":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T09:39:35Z","timestamp":1603964375000},"page":"448-457","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Celiac disease in children with type 1 diabetes varies around the world: An international, cross\u2010sectional study of 57\u2009375 patients from the <scp>SWEET<\/scp> registry"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0514-9181","authenticated-orcid":false,"given":"Anna","family":"Taczanowska","sequence":"first","affiliation":[{"name":"Department of Pediatrics Medical University of Warsaw  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anke","family":"Schwandt","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology and Medical Biometry, ZIBMT Ulm University  Ulm Germany"},{"name":"German Centre for Diabetes Research (DZD)  Munich\u2010Neuherberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shazhan","family":"Amed","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"T\u00f3th\u2010Heyn","sequence":"additional","affiliation":[{"name":"Ist Department of Pediatrics Semmelweis University  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Kanaka\u2010Gantenbein","sequence":"additional","affiliation":[{"name":"Agia Sophia Children's Hospital, First Department of Pediatrics National and Kapodistrian University of Athens Medical School  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sari Krepel","family":"Volsky","sequence":"additional","affiliation":[{"name":"Schneider Children's Medical Center of Israel Endocrinology and Diabetes  Petah Tikva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jannet","family":"Svensson","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Adolescents Copenhagen University Hospital  Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Szypowska","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Medical University of Warsaw  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12373"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12740"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1753-0407.12856"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2018.09.007"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000369518"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-2508"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000227275"},{"key":"e_1_2_8_9_1","first-page":"1","article-title":"Type 1 diabetes mellitus and celiac disease: distinct autoimmune disorders that share common pathogenic mechanisms","volume":"8","author":"Goodwin G","year":"2019","journal-title":"Horm Res Paediatr"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.5812\/ijem.66801"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-0683"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.12329"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12092"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7895207"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1530\/EC-19-0146"},{"key":"e_1_2_8_16_1","unstructured":"https:\/\/www.sweet-project.org."},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12416"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-007-0789-7"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12701"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12698"},{"key":"e_1_2_8_21_1","unstructured":"World Health Organization.WHO growth reference 5\u201319\u2009years: BMI\u2010for\u2010age (5\u201319\u2009years).2007.http:\/\/www.who.int\/growthref\/who2007_bmi_for_age\/en\/index.html. Accessed April 29 2016"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-18-0515"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.60"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31796-8"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2012.03720.x"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520510011498"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.04.007"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2012.00878.x"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-14-99"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12629"},{"key":"e_1_2_8_31_1","first-page":"11","article-title":"Coexistence of coeliac disease and type 1 diabetes","volume":"9","author":"Szaflarska\u2010Pop\u0142awska A","year":"2014","journal-title":"Prz Gastroenterol"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-0683"},{"key":"e_1_2_8_33_1","first-page":"165","article-title":"Celiac disease in children with type 1 diabetes: impact of gluten free diet on diabetes management","volume":"81","author":"Sponzilli I","year":"2010","journal-title":"Acta Biomed"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-011-0301-1"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.29"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2018.07.031"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13974"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-016-2641-3"}],"container-title":["Journal of Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1753-0407.13126","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1753-0407.13126","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1753-0407.13126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T20:52:57Z","timestamp":1693601577000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1753-0407.13126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,30]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1111\/1753-0407.13126"],"URL":"https:\/\/doi.org\/10.1111\/1753-0407.13126","archive":["Portico"],"relation":{},"ISSN":["1753-0393","1753-0407"],"issn-type":[{"value":"1753-0393","type":"print"},{"value":"1753-0407","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,30]]},"assertion":[{"value":"2020-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}