{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T14:55:21Z","timestamp":1772204121840,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T00:00:00Z","timestamp":1714953600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Diabetes"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To explore associations between type and number of abnormal glucose values on antenatal oral glucose tolerance test (OGTT) with postpartum diabetes in South Asian women diagnosed with gestational diabetes (GDM) using International Association of the Diabetes and Pregnancy Study Groups criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This post\u2010hoc evaluation of the Lifestyle Intervention IN Gestational Diabetes (LIVING) study, a randomized controlled trial, was conducted among women with GDM in the index pregnancy, across 19 centers in Bangladesh, India, and Sri Lanka. Postpartum diabetes (outcome) was defined on OGTT, using American Diabetes Association (ADA) criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We report data on 1468 women with GDM, aged 30.9 (5.0) years, and with median (interquartile range) follow\u2010up period of 1.8 (1.4\u20132.4) years after childbirth following the index pregnancy. We found diabetes in 213 (14.5%) women with an incidence of 8.7 (7.6\u201310.0)\/100 women\u2010years. The lowest incidence rate was 3.8\/100 women years, in those with an isolated fasting plasma glucose (FPG) abnormality, and highest was 19.0\/100 women years in participants with three abnormal values. The adjusted hazard ratios for two and three abnormal values compared to one abnormal value were 1.73 (95% confidence interval [CI], 1.18\u20132.54; <jats:italic>p<\/jats:italic>\u2009=\u2009.005) and 3.56 (95% CI, 2.46\u20135.16; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) respectively. The adjusted hazard ratio for the combined (combination of fasting and postglucose load) abnormalities was 2.61 (95% CI, 1.70\u20134.00; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001), compared to isolated abnormal FPG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Risk of diabetes varied significantly depending upon the type and number of abnormal values on antenatal OGTT. These data may inform future precision medicine approaches such as risk prediction models in identifying women at higher risk and may guide future targeted interventions.<\/jats:p><jats:p><jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/jdb13559-gra-0001-m.png\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p><\/jats:sec>","DOI":"10.1111\/1753-0407.13559","type":"journal-article","created":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T07:59:39Z","timestamp":1714982379000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Antenatal oral glucose tolerance test abnormalities in the prediction of future risk of postpartum diabetes in women with gestational diabetes: Results from the <scp>LIVING<\/scp> study"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4345-717X","authenticated-orcid":false,"given":"Yashdeep","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Metabolism All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deksha","family":"Kapoor","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josyula K.","family":"Lakshmi","sequence":"additional","affiliation":[{"name":"George Institute for Global Health  Hyderabad India"},{"name":"Faculty of Medicine and Health University of New South Wales  Sydney New South Wales Australia"},{"name":"Prasanna School of Public Health Manipal Academy of Higher Education  Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devarsetty","family":"Praveen","sequence":"additional","affiliation":[{"name":"George Institute for Global Health  Hyderabad India"},{"name":"Faculty of Medicine and Health University of New South Wales  Sydney New South Wales Australia"},{"name":"Prasanna School of Public Health Manipal Academy of Higher Education  Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph Alvin","family":"Santos","sequence":"additional","affiliation":[{"name":"George Institute for Global Health  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Billot","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health University of New South Wales  Sydney New South Wales Australia"},{"name":"George Institute for Global Health  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6016-5603","authenticated-orcid":false,"given":"Aliya","family":"Naheed","sequence":"additional","affiliation":[{"name":"Initiative for Non Communicable Diseases, Nutrition Research Division International Centre for Diarrhoeal Disease Research (ICDDR, B)  Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. Asita","family":"de Silva","sequence":"additional","affiliation":[{"name":"Clinical Trials Unit, Department of Pharmacology, Faculty of Medicine University of Kelaniya  Kelaniya Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ishita","family":"Gupta","sequence":"additional","affiliation":[{"name":"Centre for Chronic Disease Control  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noshin","family":"Farzana","sequence":"additional","affiliation":[{"name":"Initiative for Non Communicable Diseases, Nutrition Research Division International Centre for Diarrhoeal Disease Research (ICDDR, B)  Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renu","family":"John","sequence":"additional","affiliation":[{"name":"George Institute for Global Health  Hyderabad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saumiyah","family":"Ajanthan","sequence":"additional","affiliation":[{"name":"RemediumOne  Colombo Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neerja","family":"Bhatla","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankush","family":"Desai","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Goa Medical College  Goa India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arunasalam","family":"Pathmeswaran","sequence":"additional","affiliation":[{"name":"Department of Public Health, Faculty of Medicine University of Kelaniya  Ragama Sri 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