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Age\u2010period\u2010cohort analysis was used to assess burden trends from 1990 to 2021, identify risk factor population attributable fractions (PAFs), and project the burden through 2036.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 2021, there were 20\u2009911\u2009520 CKD\u2010T2D cases in China, with an age\u2010standardized prevalence rate (ASPR) of 1053.92 per 100\u2009000, an incidence rate (ASIR) of 23.07, an age\u2010standardized mortality rate (ASMR) of 5.72, and an age\u2010standardized DALY rate (ASDR) of 122.15. Although the overall burden showed a slow decline from 1990 to 2021, incidence continued to rise. The 2021 data revealed a marked age effect, with the burden rising with age. Period effects also contributed to an increased risk, with metabolic risk factors such as high fasting plasma glucose and BMI contributing the most. Projections suggest a decline in mortality and DALYs by 2036, while incidence will keep increasing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite declines in ASMR and ASDR, CKD\u2010T2D incidence and cases continue to rise, especially among males and the elderly. This increasing burden is driven by aging and metabolic risk factors. Early screening, education, and risk management are essential for addressing CKD\u2010T2D in China.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1753-0407.70084","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T10:15:07Z","timestamp":1745403307000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Trends and Disparities in the Burden of Chronic Kidney Disease due to Type 2 Diabetes in China From 1990 to 2021: A Population\u2010Based Study"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4814-6514","authenticated-orcid":false,"given":"Yifei","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency\u2010Stasis\u2010Turbidity Disease  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiya","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency\u2010Stasis\u2010Turbidity Disease  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixuan","family":"Xie","sequence":"additional","affiliation":[{"name":"Institute of Chronic Nephropathy Wenzhou Medical University  Wenzhou Zhejiang China"},{"name":"Department of Nephrology The First Affiliated Hospital of Wenzhou Medical University  Wenzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyong","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Nephrology, XianJu People's Hospital, Zhejiang Southeast Campus of Zhejiang Provincial People's Hospital Affiliated Xianju's Hospital, Hangzhou Medical College  Xianju Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenfang","family":"He","sequence":"additional","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency\u2010Stasis\u2010Turbidity Disease  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yexiang","family":"Chen","sequence":"additional","affiliation":[{"name":"The Third Clinical Medical College Zhejiang Chinese Medical University  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Nephrology The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)  Hangzhou Zhejiang China"},{"name":"Zhejiang Key Laboratory of Research and Translation for Kidney Deficiency\u2010Stasis\u2010Turbidity Disease  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3811-8226","authenticated-orcid":false,"given":"Qiang","family":"He","sequence":"additional","affiliation":[{"name":"Institute of Chronic Nephropathy Wenzhou Medical University  Wenzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,23]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"US Department of Health and Human Services CfDCaP \u201cNational Diabetes Statistics Report \u201d 2020 https:\/\/www.cdc.gov\/diabetes\/pdfs\/data\/statistics\/national\u2010diabetes\u2010statistics\u2010report.pdf."},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2020.05.005"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2022.05.003"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30788-2"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.01.001"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2015.02.008"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2022.05.012"},{"key":"e_1_2_11_9_1","unstructured":"M. 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