{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T03:52:28Z","timestamp":1775965948230,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,3,26]],"date-time":"2013-03-26T00:00:00Z","timestamp":1364256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2013,10]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>The aim of this study is to compare the results of positron emission tomography (PET<\/jats:styled-content>)\/CT<\/jats:styled-content> with bremsstrahlung imaging following Y<\/jats:styled-content>\u201090 radiation synovectomy.<\/jats:p><\/jats:sec>Methods<\/jats:title>All patients referred to our institution for Y<\/jats:styled-content>\u201090 radiation synovectomy between J<\/jats:styled-content>uly 2011 and F<\/jats:styled-content>ebruary 2012 underwent both PET<\/jats:styled-content>\/CT<\/jats:styled-content> and bremsstrahlung planar (\u00b1\u2009single photon emission computed tomography (SPECT<\/jats:styled-content>) or SPECT<\/jats:styled-content>\/CT<\/jats:styled-content>) imaging at 4 or 24\u2009h following administration of Y<\/jats:styled-content>\u201090 silicate colloid. PET<\/jats:styled-content> image acquisition was performed for between 15 and 20\u2009min. In patients who underwent SPECT<\/jats:styled-content>, side\u2010by\u2010side comparison with PET<\/jats:styled-content> was performed and image quality\/resolution scored using a five\u2010point scale. The distribution pattern of Y<\/jats:styled-content>\u201090 on PET<\/jats:styled-content> and bremsstrahlung imaging was compared with the intra\u2010 or extra\u2010articular location of Y<\/jats:styled-content>\u201090 activity on fused PET<\/jats:styled-content>\/CT<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>Thirteen joints (11 knees and two ankles) were imaged with both PET<\/jats:styled-content>\/CT<\/jats:styled-content> and planar bremsstrahlung imaging with 12 joints also imaged with bremsstrahlung SPECT<\/jats:styled-content>. Of the 12 joints imaged with SPECT<\/jats:styled-content>, PET<\/jats:styled-content> image quality\/resolution was superior in 11 and inferior in one. PET<\/jats:styled-content> demonstrated a concordant distribution pattern compared with bremsstrahlung imaging in all scans, with the pattern classified as diffuse in 12 and predominantly focal in one. In all 12 diffuse scans, PET<\/jats:styled-content>\/CT<\/jats:styled-content> confirmed the Y<\/jats:styled-content>\u201090 activity to be located intra\u2010articularly. In the one predominantly focal scan, the fused PET<\/jats:styled-content>\/CT<\/jats:styled-content> images localised the Y<\/jats:styled-content>\u201090 activity to mostly lie in the extra\u2010articular space of the knee.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>PET<\/jats:styled-content>\/CT<\/jats:styled-content> can provide superior image quality compared with bremsstrahlung imaging and may enable reliable detection of extra\u2010articular Y<\/jats:styled-content>\u201090 activity when there are focal patterns on planar bremsstrahlung imaging.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.12049","type":"journal-article","created":{"date-parts":[[2013,3,26]],"date-time":"2013-03-26T13:39:07Z","timestamp":1364305147000},"page":"567-571","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparison of positron emission tomography\/CT<\/scp> and bremsstrahlung imaging following Y<\/scp>\u201090 radiation synovectomy"],"prefix":"10.1111","volume":"57","author":[{"given":"Thomas W.","family":"Barber","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine & PET Centre The Alfred Hospital Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth S. K.","family":"Yap","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine & PET Centre The Alfred Hospital Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin H.","family":"Cherk","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine & PET Centre The Alfred Hospital Melbourne Australia"},{"name":"Department of Medicine Monash University, Alfred Hospital Campus Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Powell","sequence":"additional","affiliation":[{"name":"Department of Rheumatology The Alfred Hospital Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Kalff","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine & PET Centre The Alfred Hospital Melbourne Australia"},{"name":"Department of Medicine Monash University, Alfred Hospital Campus Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,26]]},"reference":[{"issue":"6","key":"e_1_2_5_2_1","first-page":"Suppl: 3\u20109","article-title":"Characteristics of radio\u2010isotopes for intra\u2010articular therapy","volume":"32","author":"Ingrand J","year":"1973","journal-title":"Ann Rheum Dis"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-002-1058-0"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2005.047373"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apradiso.2006.08.009"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.110.080986"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-009-1210-1"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-009-1317-4"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-011-2058-8"},{"key":"e_1_2_5_10_1","doi-asserted-by":"crossref","first-page":"N39","DOI":"10.1055\/s-0037-1621657","article-title":"Post\u2010radiosynovectomy 90Y\u2010PET imaging","volume":"50","author":"Prechtel HW","year":"2011","journal-title":"Nuklearmedizin"},{"key":"e_1_2_5_11_1","first-page":"51","article-title":"Samarium\u2010153\u2010particulate hydroxyapatite radiation synovectomy: biodistribution data for chronic knee synovitis","volume":"36","author":"Clunie G","year":"1995","journal-title":"J Nucl Med"}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1754-9485.12049","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.12049","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T04:38:20Z","timestamp":1696221500000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1754-9485.12049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,26]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1111\/1754-9485.12049"],"URL":"https:\/\/doi.org\/10.1111\/1754-9485.12049","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"value":"1754-9477","type":"print"},{"value":"1754-9485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,26]]},"assertion":[{"value":"2012-10-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-01-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-03-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}