{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:28:56Z","timestamp":1792272536999,"version":"4.4.0"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,10,4]],"date-time":"2013-10-04T00:00:00Z","timestamp":1380844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Androgen deprivation therapy (<jats:styled-content style=\"fixed-case\">ADT<\/jats:styled-content>) is an important component of modern prostate cancer treatment. Survival benefits from neo\u2010adjuvant and adjuvant hormones may take years to manifest, and balancing this with potential morbidity of therapy can be challenging. This study aimed to assess whether education and short\u2010term combined aerobic and resistance exercises could help to ameliorate the adverse side effects of <jats:styled-content style=\"fixed-case\">ADT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eight hundred fifty\u2010nine patients with relapsed or metastatic prostate cancer on leuprorelin acetate were allocated to three interventional streams based on patient preference and medical fitness: supervised group (Face\u2010to\u2010Face) exercise sessions, home\u2010based (At Home) exercise or a support programme for those incapable of exercising (Support). Patients enrolled onto Face to Face underwent measurement of body composition and cardiorespiratory fitness variables at baseline and programme completion. Patients in the exercise streams were surveyed to determine the programme's impact on physical fitness and well\u2010being.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Statistically significant improvements (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) were seen in all measured cardiorespiratory fitness and strength variables. Programme attrition rates were low (75\/859; 8.7%), the primary reason for withdrawal being discontinuation of hormones (70%). Programme satisfaction was high, with 98% of surveyed patients reporting a positive impact on fitness and 97% planning to continue exercising after programme completion. At 6 months, improved physical and emotional well\u2010being was reported by 93 and 79% of patients, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A short\u2010term structured exercise intervention results in high compliance and significant improvements in muscle strength and cardiorespiratory fitness in prostate cancer patients on <jats:styled-content style=\"fixed-case\">ADT<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.12115","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T02:17:40Z","timestamp":1381544260000},"page":"369-376","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Prospective study of exercise intervention in prostate cancer patients on androgen deprivation therapy"],"prefix":"10.1111","volume":"58","author":[{"given":"Nadine","family":"Beydoun","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology St George Hospital  Kogarah New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph A.","family":"Bucci","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology St George Hospital  Kogarah New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaw S.","family":"Chin","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology St George Hospital  Kogarah New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Spry","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Sir Charles Gairdner Hospital  Nedlands Western Australia Australia"},{"name":"Faculty of Medicine, University of Western Australia  Nedlands Western Australia Australia"},{"name":"Edith Cowan University Health and Wellness Institute Edith Cowan University  Joondalup Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Newton","sequence":"additional","affiliation":[{"name":"Edith Cowan University Health and Wellness Institute Edith Cowan University  Joondalup Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel A.","family":"Galv\u00e3o","sequence":"additional","affiliation":[{"name":"Edith Cowan University Health and Wellness Institute Edith Cowan University  Joondalup Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01579-6"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09408-4"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/pcan.2009.12"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.06.2497"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djm168"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.09.3369"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-2507"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1042\/CS20020209"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.87.2.8299"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.07539.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.9.7851"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijir.3901471"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23440"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.35.1494"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.9.7838"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.09.066"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.20341"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.2488"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-199407000-00003"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)12355-8"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.9.981"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a010205"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-008-0065-1"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0b013e3180616aa2"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.17.2018"},{"key":"e_1_2_6_27_1","first-page":"130","article-title":"Sarcopenia. Exercise as a treatment strategy","volume":"35","author":"Taaffe DR","year":"2006","journal-title":"Aust Fam Physician"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a439"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.09.534"}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1754-9485.12115","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.12115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T08:10:04Z","timestamp":1696234204000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1754-9485.12115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,4]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/1754-9485.12115"],"URL":"https:\/\/doi.org\/10.1111\/1754-9485.12115","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"value":"1754-9477","type":"print"},{"value":"1754-9485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,4]]},"assertion":[{"value":"2013-07-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-08-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}