{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T11:54:17Z","timestamp":1789386857827,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,7]],"date-time":"2014-03-07T00:00:00Z","timestamp":1394150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2014,8]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>The traditional view is that spontaneous extracranial internal carotid artery (ICA<\/jats:styled-content>) dissection (CAD<\/jats:styled-content>) extends cranially from an intimal tear located just beyond the carotid bulb. This paper demonstrates that CAD<\/jats:styled-content> originates in and primarily involves a more distal segment of the artery.<\/jats:p><\/jats:sec>Methods<\/jats:title>A retrospective study of 54 dissected ICAs<\/jats:styled-content> in 50 consecutive patients with spontaneous or traumatic CAD<\/jats:styled-content> was undertaken. The site of the dissection, presence of ICA<\/jats:styled-content> redundancy, rate of acute or delayed ischaemic stroke and vessel remodelling were determined.<\/jats:p><\/jats:sec>Results<\/jats:title>Of the 51 dissections that occurred spontaneously or after indirect trauma, 25\/51 (49.0%) were solely in the distal third of the artery, and 49\/51 (96.1%) involved the distal two\u2010thirds. Only 2\/51 (3.9%) originated in the proximal third. ICA<\/jats:styled-content> redundancy was seen in 27\/36 (75%) of patients with spontaneous CAD<\/jats:styled-content>, compared with only 1\/11 (9.1%) of those with CAD<\/jats:styled-content> due to indirect trauma (P<\/jats:italic>\u2009=\u20090.0002). Acute stroke occurred in 10\/12 (83.3%) of patients with ICA<\/jats:styled-content> occlusion secondary to CAD<\/jats:styled-content> and in 14\/38 (36.8%) with non\u2010occlusive CAD<\/jats:styled-content> (P<\/jats:italic>\u2009=\u20090.0074). Where follow\u2010up was available, only 2\/32 (6.3%) patients had a stroke after diagnosis, and 19\/33 (57.6%) ICAs<\/jats:styled-content> recanalised or remodelled.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>CAD<\/jats:styled-content> occurring spontaneously or due to indirect trauma most frequently involves the distal extracranial ICA<\/jats:styled-content>. Spontaneous CAD<\/jats:styled-content> is associated with vessel redundancy, and the risk of acute stroke is greatest with occlusive CAD<\/jats:styled-content>. The prognosis is good with treatment, with a low rate of recurrent stroke and a high rate of vessel remodelling.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.12170","type":"journal-article","created":{"date-parts":[[2014,3,7]],"date-time":"2014-03-07T10:41:17Z","timestamp":1394188877000},"page":"408-414","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["The location of origin of spontaneous extracranial internal carotid artery dissection is adjacent to the skull base"],"prefix":"10.1111","volume":"58","author":[{"given":"Jonathon","family":"Downer","sequence":"first","affiliation":[{"name":"Neurological Intervention and Imaging Service of Western Australia Sir Charles Gairdner Hospital Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahendra","family":"Nadarajah","sequence":"additional","affiliation":[{"name":"National Neuroscience Institute Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliza","family":"Briggs","sequence":"additional","affiliation":[{"name":"Neurological Intervention and Imaging Service of Western Australia Sir Charles Gairdner Hospital Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Wrigley","sequence":"additional","affiliation":[{"name":"Neurological Intervention and Imaging Service of Western Australia Sir Charles Gairdner Hospital Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"McAuliffe","sequence":"additional","affiliation":[{"name":"Neurological Intervention and Imaging Service of Western Australia Sir Charles Gairdner Hospital Perth Western Australia Australia"},{"name":"Neurological Intervention and Imaging Service of Western Australia Royal Perth Hospital Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,3,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.59.1.26"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70084-5"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200103223441206"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00871.2010"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.22.3.195"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.6.1201"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.286085512"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.497370"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002340050668"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2599"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000159739.24607.98"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318217e71c"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2011.11.018"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5737-7"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.496760"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.639021"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.519694"},{"key":"e_1_2_6_19_1","first-page":"370","article-title":"Long\u2010term outcomes of internal carotid artery dissection","volume":"54","author":"Rao AS","year":"2011","journal-title":"YMVA"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100008556"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318264e36b"}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1754-9485.12170","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.12170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T10:40:41Z","timestamp":1696502441000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1754-9485.12170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,7]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["10.1111\/1754-9485.12170"],"URL":"https:\/\/doi.org\/10.1111\/1754-9485.12170","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"value":"1754-9477","type":"print"},{"value":"1754-9485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,7]]},"assertion":[{"value":"2013-02-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-01-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}