{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T04:16:14Z","timestamp":1744690574857},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,4,21]],"date-time":"2015-04-21T00:00:00Z","timestamp":1429574400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2015,8]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>Chronic recurrent multifocal osteomyelitis (CRMO<\/jats:styled-content>) is an auto\u2010inflammatory disease which is characterised by non\u2010infectious bone lesions at multiple sites which have a relapsing nature. Our aim is to examine the role of radiology in diagnosis and management of CRMO<\/jats:styled-content> patients who have been managed at the M<\/jats:styled-content>ater C<\/jats:styled-content>hildren's H<\/jats:styled-content>ospital.<\/jats:p><\/jats:sec>Methods<\/jats:title>This is a retrospective analysis of patients who have been managed with CRMO<\/jats:styled-content> at the M<\/jats:styled-content>ater Hospital since 2002. Inclusion criteria included a final diagnosis of CRMO<\/jats:styled-content>. Exclusion criteria were a diagnosis more likely than CRMO<\/jats:styled-content>. Medical images for each patient were evaluated for lesion features, location of lesion, number of bony lesions and whether or not the radiographic appearance would be characteristic of CRMO<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>Initially, 17 patients were included in the study; however, seven patients were excluded due to a more likely alternative diagnosis. In total, 24 lesions were detected; the most common anatomical sites were the spine (25%), feet (25%), ribs (16.7%) and femur (12.5%). Plain radiography lacked sensitivity, but it was important in initial screening and evaluating progress of lesions. MRI<\/jats:styled-content> is important for targeted investigation and further evaluation of lesions. Bone scintigraphy is useful for detecting other affected sites. Due to the exposure to radiation, computed tomography is generally avoided.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The combination of imaging modalities plays a large role in CRMO<\/jats:styled-content> diagnosis. CRMO<\/jats:styled-content> lesions usually appear ill defined with no pathognomonic features. The distribution of bony lesions can aid diagnosis, with lower limbs and clavicles commonly affected.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.12311","type":"journal-article","created":{"date-parts":[[2015,4,22]],"date-time":"2015-04-22T02:25:01Z","timestamp":1429669501000},"page":"436-444","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Chronic recurrent multifocal osteomyelitis: A rare entity"],"prefix":"10.1111","volume":"59","author":[{"given":"Gajan","family":"Surendra","sequence":"first","affiliation":[{"name":"Medical Imaging Department Mater Children's Hospital South Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umesh","family":"Shetty","sequence":"additional","affiliation":[{"name":"Medical Imaging Department Mater Children's Hospital South Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.294085244"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2523081335"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-012-0239-5"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1546-0096-11-S2-P196"},{"key":"e_1_2_10_6_1","first-page":"1778","article-title":"Bone scintigraphy in the detection of chronic recurrent multifocal osteomyelitis","volume":"39","author":"Mandell G","year":"1998","journal-title":"J Nucl Med"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.316115523"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1214160"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-8389(05)70279-7"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.323115110"}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1754-9485.12311","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1754-9485.12311","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.12311","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1754-9485.12311","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.12311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T01:52:39Z","timestamp":1694051559000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1754-9485.12311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,21]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1111\/1754-9485.12311"],"URL":"https:\/\/doi.org\/10.1111\/1754-9485.12311","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"value":"1754-9477","type":"print"},{"value":"1754-9485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,21]]},"assertion":[{"value":"2014-12-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-02-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-04-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}