{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:25:28Z","timestamp":1782433528872,"version":"3.54.5"},"reference-count":8,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T00:00:00Z","timestamp":1433376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Because acoustic neuroma (<jats:styled-content style=\"fixed-case\">AN<\/jats:styled-content>), also termed vestibular schwannoma, constitutes by far the commonest intracranial schwannoma and cerebello\u2010pontine angle (<jats:styled-content style=\"fixed-case\">CPA<\/jats:styled-content>) tumour, there is a risk of overlooking rarer alternative diagnoses with similar clinical and\/or radiological features. The purpose of this article is to highlight to radiosurgeons the potentially serious implications of this problem through illustrative case studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Our linac stereotactic radiosurgery (<jats:styled-content style=\"fixed-case\">SRS<\/jats:styled-content>) technique has been previously described, with stereotactic headring fixation and treatment delivered via cones or micro\u2010multileaf collimators using multiple arcs or static beams.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ovember 1993 and <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ctober 2014, we treated 132 patients referred with a clinical diagnosis of <jats:styled-content style=\"fixed-case\">AN<\/jats:styled-content>, the vast majority with 12\u2009Gy marginal dose. Three of these (2.3%), evident either at the time of treatment (2) or subsequently (1), had features instead consistent with cochlear schwannoma, facial schwannoma and meningioma, respectively. Each warranted significant modification to standard <jats:styled-content style=\"fixed-case\">AN<\/jats:styled-content> outlining and fields. The meningioma progressed due to geographic miss. One other patient with recurrent facial schwannoma (not yet needing <jats:styled-content style=\"fixed-case\">SRS<\/jats:styled-content>) was also referred with an incorrect diagnosis of <jats:styled-content style=\"fixed-case\">AN<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>When rare variants of common medical problems are not identified before referral, there is a risk that \u2018blinkering\u2019 can lead to misdiagnosis and suboptimal treatment. Radiosurgeons need to be particularly mindful of this issue with <jats:styled-content style=\"fixed-case\">AN<\/jats:styled-content>, which can mimic several other tumours occurring in the <jats:styled-content style=\"fixed-case\">CPA<\/jats:styled-content> region, albeit with different patterns of spread. Optimal imaging, high\u2010quality radiology reporting and neuroradiology input at the time of <jats:styled-content style=\"fixed-case\">SRS<\/jats:styled-content> planning within the setting of a specialised multidisciplinary team are highly desirable.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.12328","type":"journal-article","created":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T10:00:07Z","timestamp":1433412007000},"page":"474-479","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["When is an acoustic neuroma not an acoustic neuroma? 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