{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:14:03Z","timestamp":1779909243181,"version":"3.53.1"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,8,4]],"date-time":"2015-08-04T00:00:00Z","timestamp":1438646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>To establish the optimal planning risk volume (<jats:styled-content style=\"fixed-case\">PRV<\/jats:styled-content>) of the lenses for patients who are receiving radiotherapy to the nasal cavity and paranasal sinus (<jats:styled-content style=\"fixed-case\">NCPSC<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Geometrical uncertainties of the lenses were evaluated for a prospective group of patients (<jats:styled-content style=\"fixed-case\">G1<\/jats:styled-content>). Differences between planned and delivered maximum doses to the lenses were evaluated for every fraction. The relationship between dose differences and geometrical uncertainties were analysed to establish an optimal <jats:styled-content style=\"fixed-case\">PRV<\/jats:styled-content> for the lenses. Obtained results were verified in the second group (<jats:styled-content style=\"fixed-case\">G2<\/jats:styled-content>) of patients for whom calculated <jats:styled-content style=\"fixed-case\">PRV<\/jats:styled-content> was applied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data of 426 observations for 15 patients from <jats:styled-content style=\"fixed-case\">G1<\/jats:styled-content> were investigated. The systematic and random errors equalled, respectively, 0.6\u2009mm and 2.3\u2009mm in the medio\u2010lateral direction; 0.8\u2009mm and 1.6\u2009mm in the cranio\u2010caudal direction; and 0.4\u2009mm and 1.5\u2009mm in the anterio\u2010posterior direction. The clinical <jats:styled-content style=\"fixed-case\">PRV<\/jats:styled-content> for the lenses was established at 2\u2009mm. Applied margin was evaluated for 10 patients from <jats:styled-content style=\"fixed-case\">G2<\/jats:styled-content>. The dose distribution in the planning target volume (<jats:styled-content style=\"fixed-case\">PTV<\/jats:styled-content>) for <jats:styled-content style=\"fixed-case\">G1<\/jats:styled-content> and for <jats:styled-content style=\"fixed-case\">G2<\/jats:styled-content> was comparable (<jats:italic>P<\/jats:italic>\u2009=\u20090.122), whereas the differences between planned and delivered doses in the lenses were significantly smaller for G2 (<jats:italic>P<\/jats:italic>\u2009=\u20090.013).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study showed that for radiotherapy of <jats:styled-content style=\"fixed-case\">NCPSC<\/jats:styled-content>, the <jats:styled-content style=\"fixed-case\">PRV<\/jats:styled-content> for the lenses could be defined as 2\u2009mm. This margin does not affect the dose distribution in the <jats:styled-content style=\"fixed-case\">PTV<\/jats:styled-content> and effectively reduces the differences between planned and delivered doses in the lenses.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.12344","type":"journal-article","created":{"date-parts":[[2015,8,4]],"date-time":"2015-08-04T09:46:33Z","timestamp":1438681593000},"page":"743-750","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Estimation of the planning organ at risk volume for the lenses during radiation therapy for nasal cavity and paranasal sinus cancer"],"prefix":"10.1111","volume":"59","author":[{"given":"Tomasz","family":"Piotrowski","sequence":"first","affiliation":[{"name":"Department of Electroradiology University of Medical Sciences  Poznan Poland"},{"name":"Department of Medical Physics Greater Poland Cancer Centre  Poznan 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