{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T17:54:15Z","timestamp":1724176455292},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,11,23]],"date-time":"2015-11-23T00:00:00Z","timestamp":1448236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2016,2]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>The aim of this study was to evaluate the efficacy of diffusion\u2010weighted images (DWIs<\/jats:styled-content>) in the differentiation of hydatid cysts (HCs<\/jats:styled-content>) of the liver.<\/jats:p><\/jats:sec>Methods<\/jats:title>In this prospective study, 54 patients with 92 HC<\/jats:styled-content> lesions were evaluated. The mean apparent diffusion coefficient (ADC<\/jats:styled-content>) values of each lesion were calculated using the ADC<\/jats:styled-content> maps derived from the DWIs<\/jats:styled-content> at b<\/jats:italic>\u2010values of 50, 500 and 1000\u2009s\/mm2<\/jats:sup>. We compared the mean ADC<\/jats:styled-content> values of the different HC<\/jats:styled-content> types, which had already been classified using the sonographic criteria. A receiver operator curve (ROC<\/jats:styled-content>) analysis was used for determining the diagnostic performance of the ADC<\/jats:styled-content> values of the HC<\/jats:styled-content> types.<\/jats:p><\/jats:sec>Results<\/jats:title>When the mean ADC<\/jats:styled-content> values of each type of HC<\/jats:styled-content> were compared using each of the b<\/jats:italic>\u2010values, no statistically significant differences were obtained between (cystic echinococcosis) CE<\/jats:styled-content>1 and CE<\/jats:styled-content>2 or CE<\/jats:styled-content>3, CE<\/jats:styled-content>2 and CE<\/jats:styled-content>3, CE<\/jats:styled-content>3 and CE<\/jats:styled-content>4, or CE<\/jats:styled-content>4 and CE<\/jats:styled-content>5. In addition, the mean ADC<\/jats:styled-content> values of CE<\/jats:styled-content>1 and CE<\/jats:styled-content>2 were significantly higher than those of CE<\/jats:styled-content>4 and CE<\/jats:styled-content>5. For discrimination between types CE<\/jats:styled-content>1, CE<\/jats:styled-content>2 and CE<\/jats:styled-content>3, and types CE<\/jats:styled-content>4 and CE<\/jats:styled-content>5, the sensitivity and specificity values were, respectively, 75.9 and 89.5 for the b50 DWI<\/jats:styled-content>, 87.0 and 86.8 for the b500 DWI<\/jats:styled-content>, and 75.9 and 89.5 for the b1000 DWI<\/jats:styled-content> in the ROC<\/jats:styled-content> analysis.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Diffusion\u2010weighted imaging may be useful for providing additional data to determine the type of HC<\/jats:styled-content>, and for differentiating types CE<\/jats:styled-content>1, CE<\/jats:styled-content>2 and CE<\/jats:styled-content>3 from types CE<\/jats:styled-content>4 and 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