{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T08:00:45Z","timestamp":1781510445028,"version":"3.54.1"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T00:00:00Z","timestamp":1472169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Immunoglobulin G4\u2010related disease (IgG4\u2010<jats:styled-content style=\"fixed-case\">RD<\/jats:styled-content>) is a fibroinflammatory condition that was first recognised as a systemic disease in 2003, when patients with autoimmune pancreatitis were found to have extrapancreatic manifestations. Since 2003, IgG4\u2010<jats:styled-content style=\"fixed-case\">RD<\/jats:styled-content> has been described in a diverse range of other organs including the biliary tree, orbits, lacrimal glands, salivary glands, lungs, kidneys, aorta, retroperitoneum, lymph nodes, pachymeninges, prostate and pituitary gland. The disease frequently occurs in the absence of pancreatic involvement. The imaging manifestations of IgG4\u2010<jats:styled-content style=\"fixed-case\">RD<\/jats:styled-content> are broad and variable depending on the organ involved. The majority of individual organ appearances are non\u2010specific and differentiation between IgG4\u2010<jats:styled-content style=\"fixed-case\">RD<\/jats:styled-content> and potentially more serious conditions is not usually possible based on radiological findings in one organ alone. However, if there are simultaneous findings typical of IgG4\u2010<jats:styled-content style=\"fixed-case\">RD<\/jats:styled-content> in multiple organs then this is a key diagnostic clue and IgG4\u2010<jats:styled-content style=\"fixed-case\">RD<\/jats:styled-content> should be considered as one of the main differentials. This review article examines the spectrum of imaging appearances of IgG4\u2010<jats:styled-content style=\"fixed-case\">RD<\/jats:styled-content>. Increased awareness of the spectrum of radiological appearances of IgG4\u2010<jats:styled-content style=\"fixed-case\">RD<\/jats:styled-content> throughout the body and subsequent consideration of the condition may potentially avoid invasive treatment and lead to more prompt corticosteroid therapy.<\/jats:p>","DOI":"10.1111\/1754-9485.12511","type":"journal-article","created":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T08:47:54Z","timestamp":1472201274000},"page":"707-713","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Imaging features of immunoglobulin G4\u2010related disease"],"prefix":"10.1111","volume":"60","author":[{"given":"Jonathan","family":"Dillon","sequence":"first","affiliation":[{"name":"Medical Imaging Department St Vincent's Hospital Melbourne Victoria 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