{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T18:14:44Z","timestamp":1784225684999,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T00:00:00Z","timestamp":1476748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Dermatofibrosarcoma Protuberans (<jats:styled-content style=\"fixed-case\">DFSP<\/jats:styled-content>) is a rare malignant soft\u2010tissue neoplasm which is often misdiagnosed due to its indolent clinical course and non\u2010specific radiological appearances. An observation case series was conducted with retrospective review of clinical and radiological data of DFSP patients presenting to a major tertiary hospital in Hong Kong for radiological assessment between November 2006 and February 2016. Seven patients with confirmed histological diagnosis of <jats:styled-content style=\"fixed-case\">DFSP<\/jats:styled-content> were included. Tumour sizes at presentation ranged from 1 to 5\u00a0cm, most commonly (<jats:italic>n<\/jats:italic>\u00a0=\u00a06) occurred over chest wall and abdominal wall. History of previous local trauma or surgery was identified in the majority of cases (<jats:italic>n<\/jats:italic>\u00a0=\u00a04). There was poor correlation between pre\u2010imaging clinical diagnoses and pathological diagnoses. Local recurrence and tumour de\u2010differentiation with sarcomatous changes occurred in the minority of cases (<jats:italic>n<\/jats:italic>\u00a0=\u00a02). A\u00a0common radiological \u2018claw\u2019 sign at the lesion\/skin interface formed by elongated appendages of the tumour superficially was appreciated in most cases (<jats:italic>n<\/jats:italic>\u00a0=\u00a06). A history of previous local trauma or surgery serves as a possible etiological factor for the development of <jats:styled-content style=\"fixed-case\">DFSP<\/jats:styled-content>. High clinical suspicion for the entity is essential in its detection and differentiation from simple wound complications and local recurrence of other benign lesions. The radiological \u2018claw\u2019 sign at the lesion\/skin interface might serve as a tell\u2010tale sign for cutaneous tumour involvement. A comprehensive analysis of imaging findings in conjunction with individual clinical presentations is the key to accurate diagnoses and proper management.<\/jats:p>","DOI":"10.1111\/1754-9485.12549","type":"journal-article","created":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T11:17:03Z","timestamp":1476789423000},"page":"9-17","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Dermatofibrosarcoma Protuberans: A comprehensive review on the spectrum of clinico\u2010radiological presentations"],"prefix":"10.1111","volume":"61","author":[{"given":"Tony HT","family":"Sung","sequence":"first","affiliation":[{"name":"Department of Radiology Pamela Youde Nethersole Eastern Hospital Chai Wan Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie CW","family":"Tam","sequence":"additional","affiliation":[{"name":"Department of Radiology Pamela Youde Nethersole Eastern Hospital Chai Wan Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer LS","family":"Khoo","sequence":"additional","affiliation":[{"name":"Department of Radiology Pamela Youde Nethersole Eastern Hospital Chai Wan Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,18]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"545","article-title":"Dermatofibromes progressifs et r\u00e9cidivants ou fibrosarcomes de la peau","volume":"5","author":"Darier J","year":"1924","journal-title":"Ann Dermatol Syphiligr (Paris)"},{"key":"e_1_2_5_3_1","first-page":"77","volume-title":"World Health Organization (WHO) Classification of Tumours of Soft Tissue and Bone. 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