{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T22:06:07Z","timestamp":1748469967600},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T00:00:00Z","timestamp":1479081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Sentinel lymph node (<jats:styled-content style=\"fixed-case\">SLN<\/jats:styled-content>) biopsy is widely accepted as an important part of staging cutaneous malignant melanoma. Hybrid single photon emission computed tomography and computed tomography (SPECT\/CT) may identify additional <jats:styled-content style=\"fixed-case\">SLN<\/jats:styled-content> and provide important information to the surgeon performing <jats:styled-content style=\"fixed-case\">SLN<\/jats:styled-content> biopsy. We report our experience at a major referral centre for melanoma surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective case series of pre\u2010operative sentinel node lymphoscintigraphy for primary melanoma over a consecutive 12\u2010month period. All patients had planar imaging and hybrid <jats:styled-content style=\"fixed-case\">SPECT<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At least 1 <jats:styled-content style=\"fixed-case\">SLN<\/jats:styled-content> was successfully identified in 82 of 86 eligible patients (95.3%). These 82 patients had 144 <jats:styled-content style=\"fixed-case\">SLN<\/jats:styled-content>s (mean 1.8). There were no patients where the <jats:styled-content style=\"fixed-case\">SLN<\/jats:styled-content> was seen only with <jats:styled-content style=\"fixed-case\">SPECT<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>. Additional information was provided by <jats:styled-content style=\"fixed-case\">SPECT<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> in 32 patients (39.0%). Histology reports were available for 52 patients, 9 (17.3%) had at least 1 <jats:styled-content style=\"fixed-case\">SLN<\/jats:styled-content> positive for metastatic disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We achieved a high rate of <jats:styled-content style=\"fixed-case\">SLN<\/jats:styled-content> identification. <jats:styled-content style=\"fixed-case\">SPECT<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> was most frequently helpful when the primary melanoma was located in the head, neck and trunk. Routine use of <jats:styled-content style=\"fixed-case\">SPECT<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> during lymphoscintigraphy provides important anatomical information and may reduce the false\u2010negative rate.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.12554","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T17:31:06Z","timestamp":1479317466000},"page":"204-211","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Utility of hybrid <scp>SPECT<\/scp>\/<scp>CT<\/scp> in primary melanoma lymphoscintigraphy: A retrospective case series"],"prefix":"10.1111","volume":"61","author":[{"given":"Khimling","family":"Tew","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine PET &amp; Ultrasound Westmead Hospital Westmead New South Wales 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