{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T19:09:44Z","timestamp":1790104184868,"version":"4.0.1"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T00:00:00Z","timestamp":1483920000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Insertion of transjugular intrahepatic portosystemic shunt (<jats:styled-content style=\"fixed-case\">TIPS<\/jats:styled-content>) is an established therapeutic option to treat the complications of portal hypertension. The purpose of this study is to review the experience of a single Australian institute with <jats:styled-content style=\"fixed-case\">TIPS<\/jats:styled-content> and evaluation of result to emphasize the indication, aetiology of portal hypertension, prognostic factors, complications and survival. Use of <jats:styled-content style=\"fixed-case\">TIPS<\/jats:styled-content> as a bridge to liver transplantation was also analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A retrospective cohort study of patients treated with <jats:styled-content style=\"fixed-case\">TIPS<\/jats:styled-content> at The Western Australian Liver Transplant Unit, Sir Charles Gairdner Hospital, over a period of 12\u00a0years. Kaplan\u2013Meier method was used for survival analysis and cox\u2010regression analysis was used to analyse the predictors of survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010three patients underwent <jats:styled-content style=\"fixed-case\">TIPS<\/jats:styled-content> between January 2000 and March 2012. The cumulative survival at 1\u00a0month, 1\u00a0year and 5\u00a0years was 90%, 70.9% and 43.9%, respectively. The predictors of survival were indication (variceal bleeding versus ascites, hazard ratio 3.19, <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 95%: 1.164\u20138.794, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.024) and Model of End Stage Liver Disease score (Hazard ratio 2.513, <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 95%: 1.087\u20135.810, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.031). Patients who underwent <jats:styled-content style=\"fixed-case\">TIPS<\/jats:styled-content> as a bridge to liver transplant had a 5\u2010year survival of 71% that is comparable to the overall survival of Western Australian liver transplant unit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Transjugular intrahepatic portosystemic shunt is a safe and effective method of treatment of complications of portal hypertension. <jats:styled-content style=\"fixed-case\">TIPS<\/jats:styled-content> can be safely used as a bridging therapy to liver transplant. Despite small number of <jats:styled-content style=\"fixed-case\">TIPS<\/jats:styled-content> being performed at our institute, our technical results are comparable to the institutes with bigger number of patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.12563","type":"journal-article","created":{"date-parts":[[2017,1,10]],"date-time":"2017-01-10T04:37:00Z","timestamp":1484023020000},"page":"441-447","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Transjugular intrahepatic portosystemic shunt: Indications, complications, survival and its use as a bridging therapy to liver transplant in Western Australia"],"prefix":"10.1111","volume":"61","author":[{"given":"Puraskar","family":"Pateria","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Sir Charles Gairdner Hospital Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary P","family":"Jeffrey","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Sir Charles Gairdner Hospital Nedlands Western Australia Australia"},{"name":"School of Medicine and Pharmacology University of Western Australia Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Garas","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Sir Charles Gairdner Hospital Nedlands Western Australia Australia"},{"name":"School of Medicine and Pharmacology University of Western Australia Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Tibballs","sequence":"additional","affiliation":[{"name":"Department of Radiology Sir Charles Gairdner Hospital Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Ferguson","sequence":"additional","affiliation":[{"name":"Department of Radiology Sir Charles Gairdner Hospital Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Delriviere","sequence":"additional","affiliation":[{"name":"School of Medicine and Pharmacology University of Western Australia Nedlands Western Australia Australia"},{"name":"Department of Surgery Sir Charles Gairdner Hospital Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Medicine and Pharmacology University of Western Australia Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leon A","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Sir Charles Gairdner Hospital Nedlands Western Australia Australia"},{"name":"School of Medicine and Pharmacology University of Western Australia Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerry","family":"MacQuillan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Sir Charles Gairdner Hospital Nedlands Western Australia Australia"},{"name":"School of Medicine and Pharmacology University of Western Australia Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,1,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23383"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000083840.97061.5b"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(71)90147-4"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)90201-8"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.05.051"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2003.10.014"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20559"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000164077.77912.98"},{"key":"e_1_2_6_10_1","unstructured":"Australia and New Zealand Liver Transplant Registry.23rd registry report. 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