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Alcohol\u2010related nutritional deficiencies and electrolyte disturbance leave chronic abusers at risk of a range of demyelinating conditions to which the radiologist and clinician should always be alert. These include Wernicke's encephalopathy, Korsakoff's syndrome, Marchiafava\u2010Bignami disease and osmotic demyelination. Cerebral volume loss is also a commonly encountered neuroimaging phenomenon in chronic alcohol abusers. Neuroimaging with <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>, with a focus on <jats:styled-content style=\"fixed-case\">FLAIR<\/jats:styled-content> and diffusion\u2010weighted <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> sequences, play an important role in the diagnosis and often monitoring of these conditions. We present an educational review of these entities in terms of their clinical features, neuropathology and imaging features along with a case example of each condition.<\/jats:p>","DOI":"10.1111\/1754-9485.12572","type":"journal-article","created":{"date-parts":[[2016,12,17]],"date-time":"2016-12-17T17:02:09Z","timestamp":1481994129000},"page":"435-440","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Neuroimaging of chronic alcohol misuse"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2014-8745","authenticated-orcid":false,"given":"Caitriona","family":"Logan","sequence":"first","affiliation":[{"name":"Neuroradiology and Neurointerventional Service Department of Radiology Beaumont Hospital Beaumont Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamed","family":"Asadi","sequence":"additional","affiliation":[{"name":"Neuroradiology and 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