{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T11:29:48Z","timestamp":1788866988821,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,7,29]],"date-time":"2017-07-29T00:00:00Z","timestamp":1501286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      Dual\u2010energy X\u2010ray absorptiometry (\n                      <jats:styled-content style=\"fixed-case\">DXA<\/jats:styled-content>\n                      ) is increasingly being used to assess abnormalities in body composition associated with a wide variety of conditions including obesity, sarcopenia, diabetes, anorexia, human immunodeficiency virus lipodystrophy, malabsorption and neuromuscular disorders\n                      <jats:sub>.<\/jats:sub>\n                      The objective of this study was to determine the short\u2010term\n                      <jats:italic>in\u00a0vivo<\/jats:italic>\n                      precision and least significant change in serial body composition measurements provided by the Hologic Horizon A densitometer as there is no published, peer reviewed body composition precision data on Horizon scanners in the medical literature.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      After acquiring two new Hologic Horizon A densitometers, short term precision scanning was performed on the two scanners using different groups of 30 volunteers, who had duplicate scans with all scans performed by the same operator. Using the International Society of Clinical Densitometry's advanced precision tool, the scan data were recorded and the coefficient of variation (\n                      <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>\n                      ) and least significant change (\n                      <jats:styled-content style=\"fixed-case\">LSC<\/jats:styled-content>\n                      ) determined for total fat, lean and bone mineral content (\n                      <jats:styled-content style=\"fixed-case\">BMC<\/jats:styled-content>\n                      ) and bone mineral density (\n                      <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Coefficients of variation of 0.78% and 0.77% were achieved for total fat (\n                      <jats:styled-content style=\"fixed-case\">LSC<\/jats:styled-content>\n                      at 95% confidence 2.15%) and 0.52% and 0.40% for total lean (\n                      <jats:styled-content style=\"fixed-case\">LSC<\/jats:styled-content>\n                      at 95% confidence 1.45% and 1.11%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These results indicate that the two Horizon A scanners in this study exceeded the minimum acceptable precision values by roughly a factor of four and are therefore capable of detecting small differences in lean and fat mass of 1\u20132% between two measurements at 95% confidence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1754-9485.12646","type":"journal-article","created":{"date-parts":[[2017,7,29]],"date-time":"2017-07-29T02:37:20Z","timestamp":1501295840000},"page":"179-182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Short term\n                    <i>in\u00a0vivo<\/i>\n                    precision of whole body composition measurements on the Horizon A densitometer"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3913-886X","authenticated-orcid":false,"given":"Michael","family":"Nowitz","sequence":"first","affiliation":[{"name":"Pacific Radiology Wakefield Hospital Newtown, Wellington New Zealand"},{"name":"Department of Medicine University of Otago Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Monahan","sequence":"additional","affiliation":[{"name":"Pacific Radiology Wakefield Hospital Newtown, Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1385\/JCD:8:3:293"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2492"},{"key":"e_1_2_6_4_1","first-page":"114","article-title":"Pharmacological interventions in frailty and sarcopenia: Report by the International Conference on Frailty and Sarcopenia Task Force","volume":"4","author":"Cesari M","year":"2015","journal-title":"J Frailty Aging"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2015.04.008"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.211"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2014.06.001"},{"key":"e_1_2_6_8_1","unstructured":"Royal Australasian College of Radiologists Standards Version 10(July 2014). Available from URL:http:\/\/www.ranzcr.edu.au\/quality-a-safety\/radiology\/standards-of-practice."},{"key":"e_1_2_6_9_1","unstructured":"International Society of Clinical Densitometry's advanced precision tool. Available from URL:http:\/\/www.iscd.org\/resources\/calculators\/precision-calculator\/"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2013.08.007"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2015.05.024"},{"key":"e_1_2_6_12_1","article-title":"Enhanced precision of the New Hologic Horizon model compared with the old discovery model is less evident when fewer vertebrae are included in the analysis","author":"McNamara EA","year":"2016","journal-title":"J Clin Densitomet"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/02640414.2014.926380"}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1754-9485.12646","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.12646","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T02:03:41Z","timestamp":1695521021000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1754-9485.12646"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,29]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1111\/1754-9485.12646"],"URL":"https:\/\/doi.org\/10.1111\/1754-9485.12646","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"value":"1754-9477","type":"print"},{"value":"1754-9485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,29]]},"assertion":[{"value":"2017-04-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}