{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:19:32Z","timestamp":1767165572756,"version":"build-2238731810"},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,4,20]],"date-time":"2018-04-20T00:00:00Z","timestamp":1524182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Lymphoepithelial carcinoma (\n                    <jats:styled-content style=\"fixed-case\">LEC<\/jats:styled-content>\n                    ) is a rare malignancy of the salivary gland arising from the parotid in 80% of cases.\n                    <jats:styled-content style=\"fixed-case\">LEC<\/jats:styled-content>\n                    is indistinguishable histologically from more common non\u2010keratinising undifferentiated nasopharyngeal carcinoma (\n                    <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content>\n                    ). Up to 40% of patients with primary\n                    <jats:styled-content style=\"fixed-case\">LEC<\/jats:styled-content>\n                    present with a cervical metastasis and histological assessment of the primary lesion or nodal metastasis may be reported as\n                    <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content>\n                    . The absence of a nasopharyngeal lesion on imaging and endoscopic assessment together with a parotid mass strengthens the case for a\n                    <jats:styled-content style=\"fixed-case\">LEC<\/jats:styled-content>\n                    . A retrospective review of three cases of primary parotid\n                    <jats:styled-content style=\"fixed-case\">LEC<\/jats:styled-content>\n                    presenting to a tertiary head and neck clinic was performed. Clinical information, imaging and histopathology findings are presented in the form of a pictorial review. Two female and one male patient with an average age of 42 years presented with a neck lump. Initial pathology results were poorly differentiated carcinoma (2\/3) and possible\n                    <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content>\n                    (1\/3).\n                    <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\n                    neck revealed unilateral parotid masses with ipsilateral cervical lymphadenopathy and assessment of the nasopharynx was negative (3\/3). Resection occurred in all patients and consensus was metastatic\n                    <jats:styled-content style=\"fixed-case\">LEC<\/jats:styled-content>\n                    with parotid primary in all cases (3\/3). 2 patients are disease free, and 1 patient is deceased (as a result of disease) at the time of this report. Lymphoepithelial carcinoma is identical histologically to\n                    <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content>\n                    , this pictorial review highlights the need for clinical and radiological correlation to establish the diagnosis.\n                  <\/jats:p>","DOI":"10.1111\/1754-9485.12735","type":"journal-article","created":{"date-parts":[[2018,4,21]],"date-time":"2018-04-21T00:06:01Z","timestamp":1524269161000},"page":"355-360","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Primary lymphoepthelial carcinoma of the parotid gland, pictorial review of a rare entity"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6986-899X","authenticated-orcid":false,"given":"Arani","family":"Halder","sequence":"first","affiliation":[{"name":"Princess Alexandra Hospital Brisbane Queensland Australia"},{"name":"Faculty of Health Sciences and Medicine Bond University Gold Coast Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Sommerville","sequence":"additional","affiliation":[{"name":"Royal Brisbane and Women's Hospital Brisbane Queensland Australia"},{"name":"Faculty of Medicine and Biomedical Sciences University of Queensland Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitesh","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Princess Alexandra Hospital Brisbane Queensland Australia"},{"name":"Radiology Queensland X\u2010Ray Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,4,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.4081\/rt.2009.e16"},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"60","DOI":"10.7812\/TPP\/12.963","article-title":"Lymphoepithelial carcinoma: a case of a rare parotid gland tumor","volume":"16","author":"Tang CG","year":"2012","journal-title":"Perm J"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-8-115"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20614"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3940"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-4-23"},{"key":"e_1_2_6_8_1","first-page":"7951","article-title":"Primary lymphoepithelioma\u2010like carcinoma of salivary glands: a clinicopathological study of 21 cases","volume":"7","author":"Zhao W","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/638058"}],"updated-by":[{"DOI":"10.1111\/1754-9485.12920","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T00:00:00Z","timestamp":1564963200000}}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1754-9485.12735","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.12735","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T08:48:52Z","timestamp":1695458932000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1754-9485.12735"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,20]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1111\/1754-9485.12735"],"URL":"https:\/\/doi.org\/10.1111\/1754-9485.12735","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"value":"1754-9477","type":"print"},{"value":"1754-9485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,20]]},"assertion":[{"value":"2017-11-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}