{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T07:10:06Z","timestamp":1783062606185,"version":"3.54.6"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,8,16]],"date-time":"2018-08-16T00:00:00Z","timestamp":1534377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>To describe a novel secondary sign of subchondral insufficiency fracture of the knee, metaphyseal burst sign (soft tissue oedema in the meta\u2010epiphyseal region of the affected condyle).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An electronic database research of 7926 knee <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> examinations was performed. Forty\u2010eight scans were included in the study. The diagnosis of subchondral insufficiency fracture (<jats:styled-content style=\"fixed-case\">SIF<\/jats:styled-content>) was confirmed in a consensus review by one fellowship trained musculoskeletal (MSK) radiologist and one radiology fellow. The presence of metaphyseal burst sign was evaluated in the cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010one patients were included in the study (21 males, 20 females). The mean age was 61.5\u00a0years (range 41\u201380\u00a0years). The anatomical location was medial femoral condyle (<jats:italic>n<\/jats:italic>\u00a0=\u00a028), the lateral femoral condyle (<jats:italic>n<\/jats:italic>\u00a0=\u00a05) and medial tibial condyle (<jats:italic>n<\/jats:italic>\u00a0=\u00a08).<\/jats:p><jats:p>The metaphyseal burst sign was present in 45 of the 48 scans reviewed. The average craniocaudal length of the soft tissue oedema defined as metaphyseal burst sign was 7\u00a0cm (range 10.5 to 4.5).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The metaphyseal burst sign is an early, indirect sign of <jats:styled-content style=\"fixed-case\">SIF<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.12781","type":"journal-article","created":{"date-parts":[[2018,8,16]],"date-time":"2018-08-16T10:29:10Z","timestamp":1534415350000},"page":"764-768","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Metaphyseal burst sign: A secondary sign on <scp>MRI<\/scp> of subchondral insufficiency fracture of the knee"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1394-1400","authenticated-orcid":false,"given":"Alessandro","family":"Vidoni","sequence":"first","affiliation":[{"name":"Radiology Department Royal Orthopaedic Hospital NHS Foundation Trust Northfield, Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachit","family":"Shah","sequence":"additional","affiliation":[{"name":"Radiology Department Royal Orthopaedic Hospital NHS Foundation Trust Northfield, Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davina","family":"Mak","sequence":"additional","affiliation":[{"name":"Radiology Department Royal Orthopaedic Hospital NHS Foundation Trust Northfield, Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Beale","sequence":"additional","affiliation":[{"name":"Heath Lodge Clinic Solihull UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sioned","family":"Beale","sequence":"additional","affiliation":[{"name":"Heath Lodge Clinic Solihull UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"James","sequence":"additional","affiliation":[{"name":"Radiology Department Royal Orthopaedic Hospital NHS Foundation Trust Northfield, Birmingham UK"},{"name":"Heath Lodge Clinic Solihull UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Botchu","sequence":"additional","affiliation":[{"name":"Radiology Department Royal Orthopaedic Hospital NHS Foundation Trust Northfield, Birmingham UK"},{"name":"Heath Lodge Clinic Solihull UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1970.03170310049013"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200006000-00013"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002560050007"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-002-1775-6"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2004.02.009"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199708000-00014"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2004.04.001"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002560000290"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2006.10.012"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2004.01.018"},{"key":"e_1_2_5_12_1","first-page":"598","article-title":"Spontaneous osteonecrosis","volume":"9","author":"Griffiths H","year":"1986","journal-title":"Orthopedics"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2008.10.010"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-004-0783-9"},{"key":"e_1_2_5_15_1","first-page":"6","article-title":"Osteonecrosis of the knee: review","volume":"3","author":"Karim AR","year":"2015","journal-title":"Ann Transl Med"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.170.1.9423603"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-8389(02)00051-9"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2009.03.012"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900480"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40634-016-0042-8"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465980260031201"}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1754-9485.12781","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.12781","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T11:16:21Z","timestamp":1694776581000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1754-9485.12781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,16]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1111\/1754-9485.12781"],"URL":"https:\/\/doi.org\/10.1111\/1754-9485.12781","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"value":"1754-9477","type":"print"},{"value":"1754-9485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,16]]},"assertion":[{"value":"2018-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}