{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T21:37:45Z","timestamp":1768340265476,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,3]],"date-time":"2019-07-03T00:00:00Z","timestamp":1562112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The purpose of this retrospective study was to evaluate imaging features of undifferentiated carcinoma of the pancreas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study group included eight patients with surgically resected undifferentiated carcinoma of the pancreas. Multidetector\u2010row computed tomography (<jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content>,<jats:italic> n<\/jats:italic>\u00a0=\u00a08) and magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>,<jats:italic> n<\/jats:italic>\u00a0=\u00a06) findings were retrospectively reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>On <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content>, all eight cases were hypovascular with upstream main pancreatic duct (<jats:styled-content style=\"fixed-case\">MPD<\/jats:styled-content>) dilatation, and only 1 showed exophytic growth. Five cases (62.5%) showed necrosis\/cystic change, and calcification was observed in two cases (25%). Calcification reflected tumour osteoid components. On <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>, haemorrhage and hemosiderin were observed in 4 of 6 (66.7%) cases. In addition, tumour thrombus in the splenic vein (<jats:italic>n<\/jats:italic>\u00a0=\u00a01) and intraductal tumour growth in the <jats:styled-content style=\"fixed-case\">MPD<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a02) were pathologically identified, although imaging studies only revealed 1 of these latter cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Undifferentiated carcinoma of the pancreas may present as a tumour with haemorrhagic necrosis. Coexistence of calcification, intraductal tumour growth in the <jats:styled-content style=\"fixed-case\">MPD<\/jats:styled-content> and tumour thrombus may support the imaging diagnosis of this entity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.12925","type":"journal-article","created":{"date-parts":[[2019,7,3]],"date-time":"2019-07-03T09:56:48Z","timestamp":1562147808000},"page":"580-588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Imaging features of undifferentiated carcinoma of the pancreas"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8107-5570","authenticated-orcid":false,"given":"Kousei","family":"Ishigami","sequence":"first","affiliation":[{"name":"Department of Clinical Radiology Graduate School of Medical Sciences Kyushu University Fukuoka 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