{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T16:48:50Z","timestamp":1791650930004,"version":"4.3.4"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T00:00:00Z","timestamp":1605139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Recently, standardized uptake value (SUV) has been applied for the evaluation of SPECT\u2010CT. This study was performed to investigate the bone SPECT\u2010CT peak SUV for chronic osteomyelitis, osteoradionecrosis and medication\u2010related osteonecrosis of the jaw (MRONJ).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010five patients with jaw lesions (12 chronic osteomyelitis, 12 osteoradionecrosis and 41 MRONJ) underwent SPECT\u2010CT after injection of technetium\u201099m hydroxymethylene diphosphonate. The peak SUV was compared for the chronic osteomyelitis with osteoradionecrosis and MRONJ using GI\u2010BONE software. Statistical analyses for the peak SUV were performed by one\u2010way repeated measures analysis of variance with Tukey's HSD test. A <jats:italic>P<\/jats:italic>\u2010value lower than 0.05 was considered as statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Peak SUV for chronic osteomyelitis (15.6\u00a0\u00b1\u00a04.4) was significantly higher than those for osteoradionecrosis (6.7\u00a0\u00b1\u00a02.1, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.000) and MRONJ (10.7\u00a0\u00b1\u00a06.1, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.019).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The SPECT\u2010CT peak SUV using GI\u2010BONE software can be useful for the evaluation of jaw lesions, such as chronic osteomyelitis, osteoradionecrosis and MRONJ.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.13127","type":"journal-article","created":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T17:54:47Z","timestamp":1605203687000},"page":"160-165","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Bone single\u2010photon emission computed tomography\u2010CT peak standardized uptake value for chronic osteomyelitis, osteoradionecrosis and medication\u2010related osteonecrosis of the jaw"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0832-4619","authenticated-orcid":false,"given":"Yoshiyuki","family":"Minami","sequence":"first","affiliation":[{"name":"Quantitative Diagnostic Imaging Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics Course of Applied Science The Nippon Dental University Graduate School of Life Dentistry at Niigata Niigata Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9169-8429","authenticated-orcid":false,"given":"Ichiro","family":"Ogura","sequence":"additional","affiliation":[{"name":"Quantitative Diagnostic Imaging Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics Course of Applied Science The Nippon Dental University Graduate School of Life Dentistry at Niigata Niigata Japan"},{"name":"Department of Oral and Maxillofacial Radiology The Nippon Dental University School of Life Dentistry at Niigata Niigata 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