{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:02:51Z","timestamp":1784764971258,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T00:00:00Z","timestamp":1609200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1132471"],"award-info":[{"award-number":["APP1132471"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Recent advances in image guidance and adaptive radiotherapy could enable gantry\u2010free radiotherapy using patient rotation. Gantry\u2010free radiotherapy could substantially reduce the cost of radiotherapy systems and facilities. MRI guidance complements a gantry\u2010free approach because of its ability to visualise soft tissue deformation during rotation. A potential barrier to gantry\u2010free radiotherapy is patient acceptability, especially when combined with MRI. This study investigates human experiences of horizontal rotation within an MRI scanner.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ten healthy human participants and nine participants previously treated with radiotherapy were rotated within an MRI scanner. Participants' anxiety and motion sickness was assessed before being rotated in 45\u2010degree increments and paused, representing a multi\u2010field intensity\u2010modulated radiotherapy treatment. An MR image was acquired at each 45\u2010degree angle. Following imaging, anxiety and motion sickness were re\u2010assessed, followed by a comfort questionnaire and exit interview. The significance of the differences in anxiety and motion sickness pre\u2010 versus post\u2010imaging was assessed using Wilcoxon signed\u2010rank tests. Content analysis was performed on exit interview transcripts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eight of ten healthy and eight of nine patient participants completed the imaging session. Mean anxiety scores before and after imaging were 7.9\/100 and 11.8\/100, respectively (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.26), and mean motion sickness scores were 5.3\/100 and 13.7\/100, respectively (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.02). Most participants indicated likely acceptance of rotation if MRI were to be used in a hypothetical treatment. Physical discomfort was reported to be the biggest concern.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Horizontal rotation within an MRI scanner was acceptable for most (17\/19) participants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.13130","type":"journal-article","created":{"date-parts":[[2020,12,30]],"date-time":"2020-12-30T09:00:26Z","timestamp":1609318826000},"page":"112-119","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Measurements of human tolerance to horizontal rotation within an MRI scanner: Towards gantry\u2010free radiation therapy"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5050-2952","authenticated-orcid":false,"given":"Jarryd G","family":"Buckley","sequence":"first","affiliation":[{"name":"Ingham Institute for Applied Medical Research Sydney New South Wales Australia"},{"name":"Centre for Medical Radiation Physics University of Wollongong Wollongong New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2496-7369","authenticated-orcid":false,"given":"Allan \u201cBen\u201d","family":"Smith","sequence":"additional","affiliation":[{"name":"Ingham Institute for Applied Medical Research Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Sidhom","sequence":"additional","affiliation":[{"name":"Liverpool and Macarthur Cancer Therapy Centre Liverpool Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0626-6438","authenticated-orcid":false,"given":"Robba","family":"Rai","sequence":"additional","affiliation":[{"name":"Liverpool and Macarthur Cancer Therapy Centre Liverpool Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary P","family":"Liney","sequence":"additional","affiliation":[{"name":"Ingham Institute for Applied Medical Research Sydney New South Wales Australia"},{"name":"Centre for Medical Radiation Physics University of Wollongong Wollongong New South Wales Australia"},{"name":"Liverpool and Macarthur Cancer Therapy Centre Liverpool Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9349-2275","authenticated-orcid":false,"given":"Jason A","family":"Dowling","sequence":"additional","affiliation":[{"name":"Centre for Medical Radiation Physics University of Wollongong Wollongong New South Wales Australia"},{"name":"CSIRO Australian eHealth Research Centre Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6820-0055","authenticated-orcid":false,"given":"Peter E","family":"Metcalfe","sequence":"additional","affiliation":[{"name":"Ingham Institute for Applied Medical Research Sydney New South Wales Australia"},{"name":"Centre for Medical Radiation Physics University of Wollongong Wollongong New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4337-2165","authenticated-orcid":false,"given":"Lois C","family":"Holloway","sequence":"additional","affiliation":[{"name":"Ingham Institute for Applied Medical Research Sydney New South Wales Australia"},{"name":"Centre for Medical Radiation Physics University of Wollongong Wollongong New South Wales Australia"},{"name":"Liverpool and Macarthur Cancer Therapy Centre Liverpool Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4803-6507","authenticated-orcid":false,"given":"Paul J","family":"Keall","sequence":"additional","affiliation":[{"name":"Ingham Institute for Applied Medical Research Sydney New South Wales Australia"},{"name":"ACRF Image\u2010X Institute School of Medicine University of Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2014.03.024"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-29999-8_25"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","unstructured":"M\u00e9nardC van derHeideU.Introduction: systems for magnetic resonance image guided radiation therapy. 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