{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T15:42:08Z","timestamp":1776958928199,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T00:00:00Z","timestamp":1625184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Certain pulmonary lesions may be challenging to biopsy with conventional computed tomography percutaneous lung biopsy (CTPLB) under local anaesthesia (LA) which requires consistent patient breath holding to minimise complications. We aim to describe and evaluate the feasibility of CTPLB under general anaesthesia (GA) with apnoea, comparing results to patients undergoing biopsy under LA. This was a retrospective analysis of CTPLB with 18 GA and 137 LA patients. All biopsies were performed using a co\u2010axial needle system in the radiology department on a multi\u2010detector CT scanner with patient positioning determined by assessing shortest distance to target lesion. GA cases were performed under relaxant anaesthesia with intermittent positive pressure ventilation. Lower lobar lesion location and a combination of size and location (including proximity to critical structures) were indications for GA biopsy in &gt;90% of patients. Mean lesion size for GA biopsies was 18\u00a0mm and control group 30\u00a0mm (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.006) and mean pleura to lesion distance 29 and 11\u00a0mm, respectively (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0009). Pneumothorax rates were lower in our GA biopsy group (11%) compared to control group (42%) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). No anaesthetic complications were encountered. All GA samples were diagnostic. Based on a small number of patients, CTPLB under GA with apnoea seems a safe, feasible alternative to conventional CTPLB under LA for technically challenging lesions. This technique is routinely employed at our centre allowing access to lesions previously deemed unsafe to biopsy.<\/jats:p>","DOI":"10.1111\/1754-9485.13279","type":"journal-article","created":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T07:48:58Z","timestamp":1625298538000},"page":"719-723","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Computed tomography guided lung biopsy under general anaesthesia with apnoea: Preliminary experience"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9339-9214","authenticated-orcid":false,"given":"Smita","family":"Deb","sequence":"first","affiliation":[{"name":"Diagnostic Imaging Monash Health Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelyn","family":"Malkoutzis","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Monash Medical Centre Monash Health Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Troupis","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging Monash Health Melbourne Victoria Australia"},{"name":"Department of Medical Imaging and Radiation Sciences Faculty of Medicine, Dentistry and Nursing Monash University Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2019.0014"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2017.07.023"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon-2018-0527"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2005.051508"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JGO.2015.002089"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2017161659"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-017-5027-1"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-016-4357-8"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-019-02196-8"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2015150381"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2012.13.2.210"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-013-0808-7"},{"key":"e_1_2_6_14_1","first-page":"5","article-title":"CT\u2010guided needle lung biopsy is possible during apneic oxygenation: a case series","volume":"8","author":"Kjaergaard B","year":"2013","journal-title":"Multidscip Respir Med"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-010-1936-y"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14565"}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.13279","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1754-9485.13279","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.13279","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T03:28:51Z","timestamp":1693279731000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1754-9485.13279"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,2]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1111\/1754-9485.13279"],"URL":"https:\/\/doi.org\/10.1111\/1754-9485.13279","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"value":"1754-9477","type":"print"},{"value":"1754-9485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,2]]},"assertion":[{"value":"2021-04-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}