{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:07:16Z","timestamp":1758474436138,"version":"3.40.5"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T00:00:00Z","timestamp":1632182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study aimed to evaluate a new 16\u2010slice SPECT\/CT scanner at Auckland City Hospital for its use in the detection and localization of parathyroid adenomas in patients with primary, secondary and tertiary hyperparathyroidism. The secondary outcome was to compare findings from SPECT\/CT with ultrasound and operative findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred patients who underwent a SPECT\/CT scan for primary\/secondary\/tertiary hyperparathyroidism were included in this study. Of these patients, 45 received surgery. SPECT\/CT and ultrasound findings were collated for each patient, and of those who received surgery, operative and pathological findings were compared with those on SPECT\/CT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sensitivity of diagnosis and localization was 86.5% (95% CI: 71.2\u201395.5%). Specificity was 25.0% (95% CI: 3.2\u201365.1%). Comparison between SPECT\/CT and ultrasound findings demonstrated a kappa coefficient of 0.203 (95% CI: \u22120.036 to 0.442), correlating with fair agreement. These figures are in line with other published series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The SPECT\/CT scanner (and associated reporters) at Auckland City Hospital demonstrates high sensitivity in the detection and localization of parathyroid adenomas and is an effective first\u2010line investigation in patients with primary\/secondary\/tertiary hyperparathyroidism.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.13330","type":"journal-article","created":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T08:34:54Z","timestamp":1632213294000},"page":"618-622","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Diagnosis and localization of parathyroid adenomas using 16\u2010slice SPECT\/CT: A clinicopathological correlation"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3378-5938","authenticated-orcid":false,"given":"Sharanya J","family":"Sankaran","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine Auckland District Health Board  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Davidson","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Auckland District Health Board  Auckland New Zealand"},{"name":"Department of Oncology University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02067389"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.06.0938"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25781"},{"key":"e_1_2_6_5_1","first-page":"127","article-title":"Comparison of SPET\/CT, SPET and planar imaging using 99mTc\u2010MIBI as independent techniques to support minimally invasive parathyroidectomy in primary hyperparathyroidism: a meta\u2010analysis","volume":"18","author":"Wei W\u2010J","year":"2015","journal-title":"Hell J Nucl Med"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2019.00164"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.107.040428"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-1870-5"},{"key":"e_1_2_6_9_1","first-page":"21","article-title":"Comparison of 99mTc\u2010MIBI planar scintigraphy, SPET\/CT and ultrasonography in detection of parathyroid adenoma in patients with primary hyperparathyroidism","volume":"23","author":"\u00d6zdemir E","year":"2020","journal-title":"Hell J Nucl Med"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0000000000000262"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0145561319828668"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2009.12.005"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0000000000001104"}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.13330","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1754-9485.13330","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.13330","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T23:34:00Z","timestamp":1692833640000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1754-9485.13330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,21]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1111\/1754-9485.13330"],"URL":"https:\/\/doi.org\/10.1111\/1754-9485.13330","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"type":"print","value":"1754-9477"},{"type":"electronic","value":"1754-9485"}],"subject":[],"published":{"date-parts":[[2021,9,21]]},"assertion":[{"value":"2021-07-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}