{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T06:42:51Z","timestamp":1775976171423,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We aimed to identify imaging\u2010based findings that can differentiate between spinal subchondral bone metastasis with focal pathologic endplate fracture and oedematous Schmorl\u2019s nodes that have been histopathologically confirmed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between March 2010 and April 2016, 11 patients who had undergone spinal magnetic resonance (MR) imaging or computed tomography (CT) with final radiologic reports that included \u2018subchondral bone metastasis with focal pathologic endplate fracture\u2019 or \u2018edematous Schmorl\u2019s node\u2019 and had also undergone percutaneous imaging\u2010guided spinal biopsies were included. Two radiologists retrospectively evaluated the following imaging features in consensus: size, location, presence of sclerotic margin, presence of intralesional or perilesional enhancement and opposite endplate enhancement of the involved disc, presence of disc height loss and presence of metabolic uptake at a corresponding lesion on nuclear medicine imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 11 patients, including six patients with spinal subchondral bone metastasis with focal pathologic endplate fracture and five patients with oedematous Schmorl\u2019s nodes, were included in this study (median age, 58\u2009years; range, 50\u201363\u2009years; six men). Sclerotic margin (<jats:italic>P<\/jats:italic>\u2009=\u20090.002) and enhancement on the opposite endplate of the involved disc (<jats:italic>P<\/jats:italic>\u2009=\u20090.047) were significantly different between oedematous Schmorl\u2019s node and subchondral bone metastasis with focal pathologic endplate fracture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sclerotic margin and enhancement on the opposite endplate of the involved disc suggest oedematous Schmorl\u2019s node rather than subchondral bone metastasis with focal pathologic endplate fracture. Decreased disc height is likely to be an oedematous Schmorl\u2019s node rather than subchondral bone metastasis with focal pathologic endplate fracture.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.13365","type":"journal-article","created":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T05:03:03Z","timestamp":1638421383000},"page":"913-919","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Differentiation between spinal subchondral bone metastasis with focal pathologic endplate fracture and oedematous Schmorl\u2019s node"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5160-390X","authenticated-orcid":false,"given":"Eunsun","family":"Oh","sequence":"first","affiliation":[{"name":"Department of Radiology Soonchunhyang University Seoul Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5386-1881","authenticated-orcid":false,"given":"Hyun\u2010joo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology Soonchunhyang University Seoul Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7656-5978","authenticated-orcid":false,"given":"Jong Won","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Radiology Dongcheondongkang Hospital  Ulsan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7822-5344","authenticated-orcid":false,"given":"Young Cheol","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Radiology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0179-9542","authenticated-orcid":false,"given":"Hyun Su","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-012-2325-9"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/1450-1147.154233"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.03.028"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0b013e31824d2516"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13139-015-0320-x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2008.03.007"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/028418519203300304"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-200211000-00013"},{"key":"e_1_2_7_10_1","first-page":"1","article-title":"Discovertebral junction of the spine\u2013a cadaveric study by spin\u2010echo MR imaging","volume":"36","author":"Kakitsubata Y","year":"1995","journal-title":"Acta Radiol"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.156.1.3923556"},{"key":"e_1_2_7_12_1","first-page":"1905","article-title":"Local spread of metastatic vertebral tumors. 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