{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T05:20:33Z","timestamp":1777785633108,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Prostatic stromal tumours of uncertain malignant potential (STUMPs) are rare prostate tumours. The purpose of this study was to investigate the magnetic resonance imaging features of STUMPs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 12 patients with STUMP confirmed with pathology who underwent MRI from 2012 to 2020 were retrospectively reviewed. Pathological characteristics including histopathology and immunohistochemistry were also recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 12 STUMPs, the tumours were detected in the peripheral zone (41.7%[<jats:italic>n<\/jats:italic>\u2009=\u20095]) and transitional zone (58.3% [<jats:italic>n<\/jats:italic>\u2009=\u20097]) of the prostate. 8 cases (66.7%) were round shape. All lesions were well\u2010defined and compressed the adjacent structures but without signs of an invasion. Homogeneous T1WI and heterogeneous T2WI signals were observed in the STUMPs. The tumours were mainly composed of solid components, while intratumoral cystic change (58.3%[<jats:italic>n<\/jats:italic>\u2009=\u20097]) and haemorrhage (8.3%[<jats:italic>n<\/jats:italic>\u2009=\u20091]) were seen. 10 cases(83.3%) were seen as relatively high DWI signal, while 2 cases(16.7%) with no increase in DWI. The mean ADC value was 1.084\u2009\u00b1\u20090.193 (range: 0.864\u20131.489\u2009\u00d7\u200910<jats:sup>\u22123<\/jats:sup>\u2009mm<jats:sup>2<\/jats:sup>\/s). STUMPs had heterogeneous enhancement, with persistent or gradual enhancement. In immunohistochemical staining, Vim, CD34, PR and SMA were positive in the majority of STUMPs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MRI features of STUMP are presented as regular, well\u2010defined and isolated prostatic mass with intact pseudocapsule. The presence of heterogeneous T2WI signal, intratumoral cystic change, slightly low mean ADC value and persistent or gradual enhancement may help predict the STUMPs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.13414","type":"journal-article","created":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T11:29:32Z","timestamp":1650972572000},"page":"1065-1072","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Magnetic resonance imaging features of prostatic stromal tumour of uncertain malignant potential"],"prefix":"10.1111","volume":"66","author":[{"given":"Yi","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Urology Peking University First Hospital  Beijing China"},{"name":"Institute of Urology Peking University  Beijing China"},{"name":"National Research Center for Genitourinary Oncology  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingyun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Radiology Peking University First Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Urology Peking University First Hospital  Beijing China"},{"name":"Institute of Urology Peking University  Beijing China"},{"name":"National Research Center for Genitourinary Oncology  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology Peking University First Hospital  Beijing China"},{"name":"Institute of Urology Peking University  Beijing China"},{"name":"National Research Center for Genitourinary Oncology  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhisong","family":"He","sequence":"additional","affiliation":[{"name":"Department of Urology Peking University First Hospital  Beijing China"},{"name":"Institute of Urology Peking University  Beijing China"},{"name":"National Research Center for Genitourinary Oncology  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liqun","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Urology Peking University First Hospital  Beijing China"},{"name":"Institute of Urology Peking University  Beijing China"},{"name":"National Research Center for Genitourinary Oncology  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6330-1060","authenticated-orcid":false,"given":"Jiangxi","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Radiology Peking University First Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,4,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200606000-00004"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAT.0b013e32835c768b"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199802000-00002"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2016.02.028"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408360390247823"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2017.155"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2016.01.002"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318214f2f2"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2013-0212-RS"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.5301\/RU.2012.9099"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/67699443"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2019.06.023"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/879584"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2011.12.4.519"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejro.2020.100233"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eucr.2014.01.008"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000010495"},{"key":"e_1_2_9_19_1","unstructured":"EAU Guidelines. 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