{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:30Z","timestamp":1791158430058,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>CT has replaced skull radiography as the gold standard for assessment of craniosynostosis in children. To minimise the risks of ionising radiation in this radiosensitive population, low\u2010dose CT protocols are increasingly being adopted. This study evaluates the effectiveness of an ultra\u2010low\u2010dose CT protocol with a tin filter in reducing radiation exposure whilst maintaining diagnostic quality for craniosynostosis, and its utility in the evaluation of other findings not appreciable on skull radiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010seven patients who underwent ultra\u2010low\u2010dose CT for craniosynostosis were compared with an age\u2010matched control group who received standard\u2010dose CT for indications other than craniosynostosis. Differences in radiation dosimetry and quantitative image quality parameters were analysed using independent two\u2010tailed <jats:italic>t<\/jats:italic>\u2010tests. Radiologist reports were also examined for the frequency of other incidental radiological findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean effective dose for the 27 ultra\u2010low\u2010dose CT scans was 0.14\u2009mSv, a 92% reduction compared with the control group. Image quality, measured by contrast\u2010to\u2010noise ratio, was significantly lower in the ultra\u2010low\u2010dose scans compared with the standard\u2010dose scans; however, all scans were diagnostic for detecting or excluding craniosynostosis. Hydrocephalus was able to be ruled out in all 27 ultra\u2010low\u2010dose scans.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ultra\u2010low\u2010dose CT with a tin filter allows for the diagnosis of craniosynostosis with a 92% dose reduction compared with the standard CT protocol. Despite lower image quality with the ultra\u2010low\u2010dose protocol when compared to standard CT, all 27 scans were adequate for craniosynostosis diagnosis. Additionally, it allowed for the assessment of other relevant findings not appreciable with skull radiography, highlighting its advantages as the new clinical standard for craniosynostosis assessment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.13812","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T10:56:00Z","timestamp":1732704960000},"page":"28-34","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of ultra\u2010low\u2010dose <scp>CT<\/scp> with tin filter for craniosynostosis"],"prefix":"10.1111","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9354-4311","authenticated-orcid":false,"given":"Wilson","family":"Tao","sequence":"first","affiliation":[{"name":"Department of Radiology Children's Hospital Westmead  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0861-3755","authenticated-orcid":false,"given":"Robert","family":"Goetti","sequence":"additional","affiliation":[{"name":"Department of Radiology Children's Hospital Westmead  Sydney New South Wales Australia"},{"name":"Faculty of Medicine and Health University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3171\/2019.7.PEDS18585"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2016.07.007"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/wdev.227"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1320064"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-019-04278-x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-017-3793-1"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.173.3.2813770"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2011.07.002"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3181cfa7ad"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph13111057"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2013.311"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814542588"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-015-3348-2"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-3870-5"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-021-05205-6"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.10100047"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2018180041"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2015.04.018"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4270"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-017-1103-x"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-013-2806-1"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-004-1220-x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.12112707"}],"container-title":["Journal of Medical Imaging and Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1754-9485.13812","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T22:02:01Z","timestamp":1740348121000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1754-9485.13812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,27]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1111\/1754-9485.13812"],"URL":"https:\/\/doi.org\/10.1111\/1754-9485.13812","archive":["Portico"],"relation":{},"ISSN":["1754-9477","1754-9485"],"issn-type":[{"value":"1754-9477","type":"print"},{"value":"1754-9485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,27]]},"assertion":[{"value":"2024-01-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}