{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T20:46:36Z","timestamp":1757623596268,"version":"3.44.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study investigates the role of positron emission tomography\u2010computed tomography in the treatment decision\u2010making process for cancer patients aged 85\u2009years and older.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective study including 137 patients. Patients aged \u2265\u200985\u2009years with histopathological solid malignancy. Demographic characteristics and comorbidities as well as performance status (ECOG), tumour characteristics, imaging modalities and treatment choices were variables. Patients were categorised according to PET\u2010CT use, and statistical analyses including Mann\u2013Whitney <jats:italic>U<\/jats:italic> test, Bonferroni correction and binary logistic regression were performed to identify independent predictors of PET\u2010CT use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The majority of patients had ECOG 2 (69%), thoracic (32%) cancer and metastatic (70%) at diagnosis, with a median age of 89\u2009years (range: 85\u201399). Comorbidities were common (73%), and the most common organ dysfunctions were renal (25%) and heart failure (24%). PET\u2010CT was performed in 47% of the patients. PET\u2010CT was predominantly used in patients with metastatic disease, those who had received radiotherapy and those who were given best supportive care. However, patients undergoing PET\u2010CT had significantly lower rates of curative treatment (3% vs. 18%, <jats:italic>p<\/jats:italic>\u2009=\u20090.0016). Binary logistic regression identified best supportive care decision as the only independent predictor of PET\u2010CT use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The findings indicated that PET\u2010CT is commonly used for staging in patients who are ultimately managed with palliative care. Future research should address the cost\u2010effectiveness of PET\u2010CT, appropriate imaging indications, and its impact on cancer\u2010related outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1754-9485.13879","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T08:14:41Z","timestamp":1751444081000},"page":"635-640","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Role of <scp>PET<\/scp>\u2010<scp>CT<\/scp> in Cancer Patients Aged 85 and Older: A Tool for Precision or Overutilisation"],"prefix":"10.1111","volume":"69","author":[{"given":"Efkan","family":"Kaya","sequence":"first","affiliation":[{"name":"Department of Pathology Adnan Menderes University Faculty of Medicine  Aydin T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0598-7284","authenticated-orcid":false,"given":"Ozgur","family":"Tanriverdi","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Mugla S\u0131tk\u0131 Ko\u00e7man University Faculty of Medicine  Mu\u011fla T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabri","family":"Barutca","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Adnan Menderes University Faculty of Medicine  Aydin T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,2]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jncc.2024.05.002"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2021.112679"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djae163"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.esmoop.2024.103965"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.55.1168"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-3-17"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2020.06.011"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21577"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2017.01.030"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.21037\/apm-20-2439"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-020-05010-7"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8588(05)70278-1"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/esmoopen-2015-000020"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon-2019-0159"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afy094"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10071518"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-018-6997-1"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-023-03138-y"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12910-023-00949-2"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1102\/1470-7330.2006.9012"},{"key":"e_1_2_13_22_1","article-title":"Changing Role of PET\/CT in Cancer Care With a Focus on Radiotherapy","volume":"14","author":"Vijayakumar S.","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/98067945"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/08998280.2005.11928089"},{"key":"e_1_2_13_25_1","first-page":"53","article-title":"Role and Cost Effectiveness of PET\/CT in Management of Patients With Cancer","volume":"83","author":"Saif M. 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