{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T12:02:10Z","timestamp":1774267330631,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T00:00:00Z","timestamp":1756166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>MRI\u2010guided adaptive radiation therapy (ART) is the resource\u2010intensive process of daily treatment plan modification. This study aims to demonstrate the feasibility of radiation therapist (RT)\u2010led MRI\u2010guided ART for oligometastatic disease (OMD) by comparing geometric accuracy and dosimetric differences between RT and radiation oncologist (RO) re\u2010contouring.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Five RTs and five ROs retrospectively re\u2010contoured gross target volumes (GTVs) and organs\u2010at\u2010risk (OARs) for eight OMD cases. RT and RO contours were compared against consensus RO Simultaneous Truth and Performance Level Estimation (RO\u2010STAPLE) contours using the Dice similarity coefficient (DICE), mean distance to agreement (MDA), planning target volume (PTV) D95 and OAR D0.5cc using the Wilcoxon signed\u2010rank test. Moreover, an RO qualitatively scored all contours using a 5\u2010point Likert scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We found very good geometric accuracy with average (\u00b1standard deviation) GTV DICE of 0.82\u2009\u00b1\u20090.06 for RTs and 0.85\u2009\u00b1\u20090.09 for ROs and MDA of 0.88\u2009\u00b1\u20090.03\u2009mm for RT and 0.75\u2009\u00b1\u20090.05\u2009mm for ROs relative to the RO\u2010STAPLE. Qualitative GTV Likert scores were excellent, 4.8\/5 for RTs and 4.7\/5 for ROs. Mean percent difference in PTV D95 compared to RO\u2010STAPLE was small but significantly higher for RTs (0.5%\u2009\u00b1\u20091.5%) compared with ROs (\u22120.7%\u2009\u00b1\u20091.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Mean relative change in OAR D0.5cc results was small with \u22121%\u2009\u00b1\u20096% for RTs and \u22121%\u2009\u00b1\u200912% for ROs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Here we provide the first report of geometric and dosimetric contouring uncertainty for MR\u2010guided online ART for OMD. Our results show that RT re\u2010contouring maintains similar performance for eligible targets and OARs compared with RO contours, establishing the initial feasibility of an RT\u2010led workflow.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1754-9485.70016","type":"journal-article","created":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T12:13:07Z","timestamp":1756210387000},"page":"777-786","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Feasibility of Therapist\u2010Driven\n                    <scp>MR<\/scp>\n                    \u2010Guided Adaptive Radiotherapy for Oligometastatic Disease: Geometric Accuracy and Dosimetric Impact"],"prefix":"10.1111","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5525-1498","authenticated-orcid":false,"given":"Amanda","family":"Moreira","sequence":"first","affiliation":[{"name":"Radiation Medicine Program, Princess Margaret Cancer Centre  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Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Hosni","sequence":"additional","affiliation":[{"name":"Radiation Medicine Program, Princess Margaret Cancer Centre  Toronto Ontario Canada"},{"name":"Department of Radiation Oncology University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aruz","family":"Mesci","sequence":"additional","affiliation":[{"name":"Radiation Medicine Program, Princess Margaret Cancer Centre  Toronto Ontario Canada"},{"name":"Department of Radiation Oncology University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Gutierrez\u2010Valencia","sequence":"additional","affiliation":[{"name":"Radiation Medicine Program, Princess Margaret Cancer Centre  Toronto Ontario Canada"},{"name":"Department of Radiation Oncology University of Toronto  Toronto Ontario 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