{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T09:54:37Z","timestamp":1791539677884,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100015650","name":"Canon Medical Systems Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015650","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018178","name":"Australasian Society for Ultrasound in Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018178","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>To assess competing US techniques in evaluation of chronic liver disease, we performed a study to determine the diagnostic accuracy of 2D\u2010shear wave elastography (2D\u2010SWE) and attenuation imaging (ATI) compared with more established methods of point shear wave elastography (pSWE) and visual B\u2010mode grading of hepatic steatosis. Magnetic resonance elastography (MRE) and proton density fat fraction (MR\u2010PDFF) were used as respective reference standards.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Fifty\u2010five patients underwent same\u2010day liver ultrasound (conventional B\u2010mode, pSWE, 2D\u2010SWE, and ATI) and 3\u2009T MRI (MRE and MR\u2010PDFF). Diagnostic performance for steatosis (mild, moderate, severe) and fibrosis (\u2265\u2009F2, \u2265\u2009F3, and F4) grades was assessed using receiver operating characteristic (ROC) curve analysis, with area under the curve (AUC) calculated. Agreement was evaluated using Cohen's kappa for categorical comparisons and intraclass correlation coefficients (ICC) for continuous measurements within the same modality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>For fibrosis, 2D\u2010SWE demonstrated high sensitivity (100%) for advanced fibrosis (\u2265\u2009F3; AUC 0.87), compared with pSWE (sensitivity of 71.4%). In contrast, pSWE showed higher specificity (92.3%) for significant fibrosis (\u2265\u2009F2) compared to 2D\u2010SWE (73.9%). Categorical agreement with MRE was higher for pSWE (kappa\u2009=\u20090.66) than 2D\u2010SWE (kappa\u2009=\u20090.45). For steatosis, visual B\u2010mode across all grades had AUC 0.85\u20130.89 compared to 0.68\u20130.85 for ATI. ATI performed best in detecting severe steatosis (AUC 0.85).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Across the spectrum of clinically relevant assessment of liver fibrosis and steatosis, pSWE and visual B\u2010mode grading showed better correlation with MRI results than 2D\u2010SWE and ATI, respectively. However, they did provide good diagnostic performance in grading liver fibrosis and steatosis in advanced disease. Further research may better define more accurate standardised cut\u2010off scores for the 2D\u2010SWE and ATI techniques.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1754-9485.70093","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T12:04:36Z","timestamp":1775217876000},"page":"611-622","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of Ultrasound Shear Wave Elastography (\n                    <scp>SWE<\/scp>\n                    ) and Attenuation Imaging (\n                    <scp>ATI<\/scp>\n                    ) for the Assessment of Hepatic Fibrosis and Steatosis\u2014A Prospective Comparison With\n                    <scp>MRI<\/scp>\n                    Liver Elastography and Proton Density Fat Fraction (\n                    <scp>PDFF<\/scp>\n                    )"],"prefix":"10.1111","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4306-3988","authenticated-orcid":false,"given":"Jessica Y.","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Medical Imaging Royal Melbourne Hospital  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayland","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Royal Melbourne Hospital  Melbourne Australia"},{"name":"Department of Medicine (Radiology) The University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Simkin","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Royal Melbourne Hospital  Melbourne Australia"},{"name":"Department of Medicine (Radiology) The University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beng Ghee","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Royal Melbourne Hospital  Melbourne Australia"},{"name":"Department of Medicine (Radiology) The University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2241-8702","authenticated-orcid":false,"given":"Damien L.","family":"Stella","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Royal Melbourne Hospital  Melbourne Australia"},{"name":"Department of Medicine (Radiology) The University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey K. C.","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Royal Melbourne Hospital  Melbourne Australia"},{"name":"Department of Medicine (Radiology) The University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddharth","family":"Sood","sequence":"additional","affiliation":[{"name":"Department of Medicine (Radiology) The University of Melbourne  Melbourne Australia"},{"name":"Department of Gastroenterology Northern Hospital  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Hng","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Western Health  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert N.","family":"Gibson","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Royal Melbourne Hospital  Melbourne Australia"},{"name":"Department of Medicine (Radiology) The University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468\u20101253(22)00165\u20100"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2025.02.034"},{"key":"e_1_2_10_4_1","first-page":"660","volume-title":"Non\u2010Invasive Diagnosis and Monitoring of Non\u2010Alcoholic Fatty Liver Disease and Non\u2010Alcoholic Steatohepatitis. 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