{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:50:38Z","timestamp":1791373838344,"version":"4.3.1"},"reference-count":55,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Med Imag Rad Onc"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Uveal melanoma is a rare but aggressive malignancy, predominantly affecting the choroid. This study is the first retrospective review performed on adult choroidal melanoma patients treated with Ruthenium\u2010106 plaque brachytherapy in Queensland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>The study period was November 2020 to January 2025, where patient, tumour, and treatment factors, as well as local control, salvage treatments, radiation retinopathy, and visual acuity were assessed at 6, 12, 24, and 36\u2009months post\u2010treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 151 patients with a mean tumour thickness of 3.85\u2009mm and mean largest basal diameter of 10.2\u2009mm received treatment. A dose of 100\u2009Gy to the tumour apex was prescribed to 88.7% of patients. The short\u2010term risk factor for disease progression was tumour thickness (odds ratio [OR] 2.01, 95% confidence interval [CI], 1.11\u20133.87;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.025), whereas tumour to optic nerve distance was a protective factor in both the short\u2010 (OR 0.55, 95% CI 0.31\u20130.82;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.013) and long\u2010term (OR 0.75, 95% CI 0.60\u20130.90;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005). At 36\u2009months post\u2010treatment, local control was 89.5%, the enucleation rate was 3.3%, tumour thickness (OR 1.77, 95% CI 1.1\u20132.98;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022) and sclera dose (OR 1.01, 95% CI 1\u20131.01;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.045) were risk factors for severe radiation retinopathy. Median visual acuity decreased by one\n                      <jats:italic>Snellen<\/jats:italic>\n                      chart line. When tumour distance to optic nerve or foveola is greater than\u20093\u2009mm, there was minimal change to visual acuity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings demonstrate that high\u2010quality plaque brachytherapy can be delivered effectively at a statewide level.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1754-9485.70200","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:00:06Z","timestamp":1791370806000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Choroidal Melanoma Treated With Ruthenium\u2010106 Eye Plaque Brachytherapy: Results of an Australian Statewide Service From November 2020 to January 2025"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9954-6908","authenticated-orcid":false,"given":"Sarah","family":"Li","sequence":"first","affiliation":[{"name":"Radiation Oncology Princess Alexandra Hospital Raymond Terrace (ROPART)  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0925-1124","authenticated-orcid":false,"given":"Lindsay A.","family":"McGrath","sequence":"additional","affiliation":[{"name":"Queensland Ocular Oncology Service at Terrace Eye Centre  Brisbane Queensland Australia"},{"name":"The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8364-9643","authenticated-orcid":false,"given":"Timothy","family":"Beckman","sequence":"additional","affiliation":[{"name":"Queensland Ocular Oncology Service at Terrace Eye Centre  Brisbane Queensland Australia"},{"name":"The 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