{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T16:44:53Z","timestamp":1757781893256,"version":"3.41.2"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,1,30]],"date-time":"2018-01-30T00:00:00Z","timestamp":1517270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["(NMRC\/CSA\u2010INV\/0001\/2016)"],"award-info":[{"award-number":["(NMRC\/CSA\u2010INV\/0001\/2016)"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovascular Therapeutics"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>The safety and efficacy of BP\u2010DES compared to second\u2010generation DP\u2010DES remain unclear in the real\u2010world setting. We compared the clinical outcomes of biodegradable polymer drug\u2010eluting stents (BP\u2010DES) with second\u2010generation durable polymer drug\u2010eluting stents (DP\u2010DES) in an all\u2010comer percutaneous coronary intervention (PCI) registry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods\/Results<\/jats:title><jats:p>The study included a cohort of 1065 patients treated with either BP\u2010DES or DP\u2010DES from January 2009 through October 2015. Propensity score matching was performed to account for potential confounders and produced 497 matched pairs of patients. The primary endpoint was target lesion failure (TLF) at one\u2010year follow\u2010up. The rates of TLF were comparable between BP\u2010DES and DP\u2010DES (8.7% vs 9.1%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.823) at 1\u00a0year. The rates of stent thrombosis at 30\u00a0days (0.4% vs 0.4%, <jats:italic>P<\/jats:italic>\u00a0=\u00a01.00) and 1\u00a0year (0.8% vs 0.8%, <jats:italic>P<\/jats:italic>\u00a0=\u00a01.00) did not differ between BP\u2010DES and DP\u2010DES. There were no significant differences in other clinical outcomes including target vessel failure (8.9% vs 9.5%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.741), in\u2010stent restenosis (1.8% vs 1.0%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.282), and cardiac death (6.4% vs 7.4%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.533) at 1\u00a0year. Multivariate cox regression analysis showed that the risk of TLF at one\u2010year did not differ significantly between BP\u2010DES and DP\u2010DES (hazard ratio 0.94, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.763).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Efficacy and safety of BP\u2010DES were not better than DP\u2010DES at one\u2010year follow\u2010up.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1755-5922.12319","type":"journal-article","created":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T08:44:02Z","timestamp":1515573842000},"source":"Crossref","is-referenced-by-count":2,"title":["A propensity score\u2010matched comparison of biodegradable polymer vs second\u2010generation durable polymer drug\u2010eluting stents in a real\u2010world population"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8820-9463","authenticated-orcid":false,"given":"Ying Jiao","family":"Zhao","sequence":"first","affiliation":[{"name":"Pharmacy and Therapeutics Office Group Corporate Development National Healthcare Group  Singapore City Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Teng","sequence":"additional","affiliation":[{"name":"Pharmacy and Therapeutics Office Group Corporate Development National Healthcare Group  Singapore City Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai Leng","family":"Khoo","sequence":"additional","affiliation":[{"name":"Pharmacy and Therapeutics Office Group Corporate Development National Healthcare Group  Singapore City Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajiv","family":"Ananthakrishna","sequence":"additional","affiliation":[{"name":"Department of Cardiology National University Heart Centre  Singapore City Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiong Cheng","family":"Yeo","sequence":"additional","affiliation":[{"name":"Department of Cardiology National University Heart Centre  Singapore City Singapore"},{"name":"Department of Medicine Yong Loo Lin School of Medicine National University of Singapore  Singapore City Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boon Peng","family":"Lim","sequence":"additional","affiliation":[{"name":"Pharmacy and Therapeutics Office Group Corporate Development National Healthcare Group  Singapore City Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua P.","family":"Loh","sequence":"additional","affiliation":[{"name":"Department of Cardiology National University Heart Centre  Singapore City Singapore"},{"name":"Department of Medicine Yong Loo Lin School of Medicine National University of Singapore  Singapore City Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark Y.","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Cardiology National University Heart Centre  Singapore City Singapore"},{"name":"Department of Medicine Yong Loo Lin School of Medicine National University of Singapore  Singapore City 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