{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T01:33:10Z","timestamp":1788831190665,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,12,7]],"date-time":"2012-12-07T00:00:00Z","timestamp":1354838400000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Epidemiological studies suggest an association between vitamin D and calcium intake and breast cancer. The aim of this study was to determine the association of breast cancer with vitamin D deficiency and osteoporosis according to menopausal status and to examine vitamin D and bone mineral density (<jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content>) levels in breast cancer patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was an observational cohort hospital\u2010based study. It included 635 patients with breast cancer. Socio\u2010demographic information, type of consanguinity, menopause status, medical history, lifestyle habits, dietary intake, <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content> measurements and vitamin D levels were collected. Descriptive and univariate analyses were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the studied patients, 36.1% were Qataris, 63.9% non\u2010Qatari Arabs, 40% premenopausal women, 20.9% university graduates and 37.2% housewives. Overall, 31.8% of breast cancer women were affected with osteopenia\/osteoporosis. Vitamin D deficiency (10.7% <jats:italic>vs<\/jats:italic>. 7.9%) and severe vitamin D insufficiency (39.2% <jats:italic>vs<\/jats:italic>. 32.5%) were higher in postmenopausal women than premenopausal women (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Low physical activity (&lt;\u00a030\u00a0min\/day) was observed among vitamin D deficient (46.8%) and osteoporotic (45%) women. Dietary intake of vitamin D was significantly lower in vitamin D deficient women; these included dairy products (33.1%), milk (38.6%), seafood (39.6%), (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and for osteoporotic women, dairy products (46%), calcium (21.3%), milk (36.1%), yoghurt (37.6%), cheese (37.6%) and sea food (34.7%) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present study findings revealed a high prevalence of vitamin D deficiency and osteoporosis in breast cancer patients. Also, the dietary intake of vitamin D and calcium was significantly lower in breast cancer women.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.12017","type":"journal-article","created":{"date-parts":[[2012,12,7]],"date-time":"2012-12-07T07:17:58Z","timestamp":1354864678000},"page":"554-561","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The role of vitamin D deficiency and osteoporosis in breast cancer"],"prefix":"10.1111","volume":"15","author":[{"given":"Abdulbari","family":"Bener","sequence":"first","affiliation":[{"name":"Department of Medical Statistics &amp; Epidemiology Hamad Medical Corporation Hamad General Hospital"},{"name":"Department of Public Health Weill Cornell Medical College Doha Qatar"},{"name":"Evidence for Population Health Unit School of Epidemiology and Health Sciences The University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanadi R.","family":"El Ayoubi","sequence":"additional","affiliation":[{"name":"Department of Oncology &amp; Hematology Al Amal Hospital Hamad Medical Corporation Doha Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/01635580701390223"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.10.1050"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00336.2004"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2008.26704"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.1.5"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.4065\/78.12.1457"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2004.03.010"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-7435(90)90058-R"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10196"},{"issue":"1","key":"e_1_2_7_11_1","first-page":"19","article-title":"Patterns of cancer incidence among the population of Qatar: a worldwide comparative study","volume":"9","author":"Bener A","year":"2007","journal-title":"Asian Pac J Cancer Prev"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2010.04.004"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.8-4-326"},{"issue":"1","key":"e_1_2_7_14_1","first-page":"15","article-title":"High prevalence of vitamin D deficiency in young children in a highly sunny humid country: a global health problem","volume":"61","author":"Bener A","year":"2009","journal-title":"Minerva Pediatr"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/94.17.1301"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1996.119"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.82.1.118"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-008-0071-6"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2005.01.017"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1207\/S15327914NC4602_05"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000103274"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-0075"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28837"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28869"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)05788-9"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.85.12.4635"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgm240"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1756-185x.12017","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185x.12017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T10:53:29Z","timestamp":1698749609000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1756-185x.12017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.1111\/1756-185x.12017"],"URL":"https:\/\/doi.org\/10.1111\/1756-185x.12017","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"value":"1756-1841","type":"print"},{"value":"1756-185X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12]]},"assertion":[{"value":"2012-12-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}