{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T03:49:46Z","timestamp":1789184986769,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,5,23]],"date-time":"2013-05-23T00:00:00Z","timestamp":1369267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the relationship between quality of life (<jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content>) and rheumatoid chachesia, malnutrition in patients with rheumatoid arthritis (<jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Euro<jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>ol <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roup 5\u2010<jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>imension <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>elf\u2010<jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>eport <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>uestionnaire (<jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>5<jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>) and <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apanese <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ealth <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ssessment <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>uestionnaire (<jats:styled-content style=\"fixed-case\">JHAQ<\/jats:styled-content>) scores, body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>), arm muscle area (<jats:styled-content style=\"fixed-case\">AMA<\/jats:styled-content>) and clinical indicators were measured in 385 <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> patients. One\u2010way analysis of variance for obtained data was conducted among three groups: 131 with low <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> (&lt;\u00a020), 163 with moderate (20\u201325) and 91 with high <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> (\u226525). Then multiple regression analyses for <jats:styled-content style=\"fixed-case\">JHAQ<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>5<jats:styled-content style=\"fixed-case\">D<\/jats:styled-content> scores with nutritional and clinical indicators as independent variables were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>5<jats:styled-content style=\"fixed-case\">D<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">JHAQ<\/jats:styled-content> scores were significantly lower and higher, respectively, in the low <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> group than those in the moderate <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> group. Clinical indicators including doses of corticosteroid were similar among the three groups except for disease duration. Disease activity score (<jats:styled-content style=\"fixed-case\">DAS<\/jats:styled-content>) 28, disease duration, <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\u2010reactive protein and <jats:styled-content style=\"fixed-case\">AMA<\/jats:styled-content> were significant variables in the regression model for <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>5<jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Low <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> deteriorates the <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> patients. Muscle protein loss apparently leads to a reduction in <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.12079","type":"journal-article","created":{"date-parts":[[2013,5,23]],"date-time":"2013-05-23T16:50:47Z","timestamp":1369327847000},"page":"297-302","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Low body mass index is associated with impaired quality of life in patients with rheumatoid arthritis"],"prefix":"10.1111","volume":"16","author":[{"given":"Wataru","family":"Fukuda","sequence":"first","affiliation":[{"name":"Department of Diabetes, Endocrinology and Rheumatology Japanese Red Cross Kyoto Daiichi Hospital Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Omoto","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Rheumatology Japanese Red Cross Kyoto Daiichi Hospital Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamaki","family":"Ohta","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Rheumatology Japanese Red Cross Kyoto Daiichi Hospital Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saori","family":"Majima","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Rheumatology Japanese Red Cross Kyoto Daiichi Hospital Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiro","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Rheumatology Japanese Red Cross Kyoto Daiichi Hospital Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Rheumatology Japanese Red Cross Kyoto Daiichi Hospital Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Kohno","sequence":"additional","affiliation":[{"name":"Inflammation and Immunology Kyoto Prefectural University of Medicine Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Kawahito","sequence":"additional","affiliation":[{"name":"Inflammation and Immunology Kyoto Prefectural University of Medicine Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,5,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.56.5.326"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-004-0377-3"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117244"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken146"},{"key":"e_1_2_8_6_1","first-page":"2350","article-title":"Relation between body mass index and radiological progression in Patients with rheumatoid arthritis","volume":"30","author":"Kaufmann J","year":"2003","journal-title":"J Rheumatol"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20612"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.14.1624"},{"key":"e_1_2_8_9_1","first-page":"S43","article-title":"The consequences of rheumatoid arthritis: quality of life measures in the individual patients","volume":"23","author":"Pollard L","year":"2005","journal-title":"Clin Exp Rheum"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-200826100-00004"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2008.00546.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfn053"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-007-0583-4"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1749-799X-2-12"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.11465"},{"key":"e_1_2_8_16_1","unstructured":"EuroQol group EQ5\u2010D user guide: a measure of health\u2010related quality of life developed by the EuroQol group. 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