{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T10:28:41Z","timestamp":1778322521901,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,12,14]],"date-time":"2013-12-14T00:00:00Z","timestamp":1386979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the clinical courses and outcomes of patients with monoarthritis and to investigate the predictive factors of clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis was performed of 171 patients with chronic monoarthritis at a single tertiary hospital between January 2001 and January 2011. Baseline characteristics, radiographic findings and the clinical course were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The most commonly involved joints were the knees (24.0%), followed by the wrists (22.8%) and ankles (18.7%). A final diagnosis was established in 74 (43.3%) patients. Thirty\u2010one (18.1%) patients were diagnosed with rheumatoid arthritis (<jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>), 23 (13.5%) with peripheral spondyloarthritis (SpA), and 19 (11.1%) with Beh\u00e7et's disease (<jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>). Among 108 patients who were initially undiagnosed, 85 (78.7%) patients remained with undiagnosed monoarthritis, with relatively shorter symptom durations and requiring less treatment. The initially involved joint was a predictive factor for the final diagnosis: the wrist joint for <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> (odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>] 11.58, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), the ankle joint for SpA (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 6.19, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), and the knee joint for <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 3.43, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.014). Bony erosion at baseline was associated with progression to oligo\u2010 or polyarthritis (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 2.88, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.030) and with radiographic progression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients presenting with monoarthritis, a final diagnosis was established in less than half of the patients, and a majority of undiagnosed patients showed benign clinical courses. The initially involved joint and the presence of erosion at baseline were predictors of the final diagnosis and of clinical outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.12259","type":"journal-article","created":{"date-parts":[[2013,12,14]],"date-time":"2013-12-14T09:04:45Z","timestamp":1387011885000},"page":"502-510","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Clinical courses and predictors of outcomes in patients with monoarthritis: a retrospective study of 171 cases"],"prefix":"10.1111","volume":"17","author":[{"given":"Hyemin","family":"Jeong","sequence":"first","affiliation":[{"name":"Department of Medicine Sungkyunkwan University School of Medicine Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ah Yeong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology Samsung Medical Center Sungkyunkwan University School of Medicine 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