{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T09:14:42Z","timestamp":1792401282054,"version":"4.4.0"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,1,17]],"date-time":"2014-01-17T00:00:00Z","timestamp":1389916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2014,7]]},"abstract":"Abstract<\/jats:title>Objectives<\/jats:title>Paraneoplastic arthritis (PA<\/jats:styled-content>) may mimic rheumatic diseases. While presenting the demographic and laboratory features of the patients diagnosed with PA<\/jats:styled-content>, this study also aims to provide possible appropriate tools to differentiate the PA<\/jats:styled-content> cases from early rheumatoid arthritis (ERA<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>Sixty\u2010five patients with PA<\/jats:styled-content> (male\/female: 43\/22) from 15 different rheumatology clinics and 50 consecutive patients with ERA<\/jats:styled-content> (male\/female: 13\/37) fulfilling the 2010 American College of Rheumatology (ACR<\/jats:styled-content>) criteria for the diagnosis if the RA<\/jats:styled-content> from Gaziantep Rheumatology Early Arthritis Trial (GREAT<\/jats:styled-content>) as controls who were diagnosed at least 12\u00a0months before, were enrolled into study.<\/jats:p><\/jats:sec>Results<\/jats:title>Mean ages of the patients with PA<\/jats:styled-content> and ERA<\/jats:styled-content> were 50.2\u00a0\u00b1\u00a015.3, and 42.7\u00a0\u00b1\u00a012.3, respectively, and the mean ages of the patients with PA<\/jats:styled-content> were significantly higher than the ERA<\/jats:styled-content>. Unlike the ERA<\/jats:styled-content> patients, in our case series PA<\/jats:styled-content> was predominantly observed among males. Oligoarthritis was significantly higher in solid tumors in contrast to ERA<\/jats:styled-content> (P\u00a0<\/jats:italic>=\u00a00.001). Polyarthritis and symmetric arthritis were significantly higher in the ERA<\/jats:styled-content> group in contrast to all malignancies (P\u00a0<\/jats:italic>=\u00a00.001). Rheumatoid factor (RF<\/jats:styled-content>) and anticyclic citrullinated peptide antibody (anti\u2010CCP<\/jats:styled-content>) positivity were significantly higher in the ERA<\/jats:styled-content> group (each P\u00a0<\/jats:italic>=\u00a00.001). Lactic dehydrogenase levels of hematologic malignancies were significantly higher than other groups (each, P\u00a0<\/jats:italic>=\u00a00.001).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>ERA<\/jats:styled-content> patients had more symmetric joint involvement than PA<\/jats:styled-content>; laboratory markers could be also an alternative where there is high RF<\/jats:styled-content> and anti\u2010CCP<\/jats:styled-content> positivity with antibody levels among the ERA<\/jats:styled-content> patients. Finally, the demographic features can be used as differentiating factors; ERA<\/jats:styled-content> was seen predominantly among females aged 40\u201359\u00a0years which refers to young adults.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.12277","type":"journal-article","created":{"date-parts":[[2014,1,17]],"date-time":"2014-01-17T05:55:29Z","timestamp":1389938129000},"page":"640-645","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Diagnostic dilemma of paraneoplastic arthritis: case series"],"prefix":"10.1111","volume":"17","author":[{"given":"Bunyamin","family":"Kisacik","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Division of Rheumatology Gaziantep University Faculty of Medicine Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet M.","family":"Onat","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division of 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