{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:01:04Z","timestamp":1791489664118,"version":"4.3.4"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,2,11]],"date-time":"2014-02-11T00:00:00Z","timestamp":1392076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Kawasaki disease (<jats:styled-content style=\"fixed-case\">KD<\/jats:styled-content>) has been associated with abnormal lipid profiles. The latter, in turn, have been linked to changes in subcutaneous fat. In this comparative cross\u2010sectional study we have quantified distribution of subcutaneous fat during follow\u2010up of a cohort of North Indian children with <jats:styled-content style=\"fixed-case\">KD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We compared 35 <jats:styled-content style=\"fixed-case\">KD<\/jats:styled-content> children (at least 2\u00a0years after disease) and 33 healthy controls. Study parameters included weight, height and skinfold thickness (<jats:styled-content style=\"fixed-case\">SFT<\/jats:styled-content>) over biceps, triceps, midaxillary, subscapular, medial calf and suprailiac areas. Waist and hip circumferences were also recorded. All parameters were measured four times at 6\u2010monthly intervals using standardized techniques. Serum lipids were assayed in the study group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Study children were enrolled 3.7\u00a0\u00b1\u00a02.5\u00a0years after KD and mean age at enrolment was 8.26\u00a0\u00b1\u00a03.65\u00a0years. Suprailiac SFT measured higher in boys with KD (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.05). Biceps SFT was higher in the study group, but the difference was not significant. Other SFT were not affected. Waist and hip circumference was higher in the study group than controls (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.05). Waist\/hip circumference ratio was not affected. Serum low\u2010density lipoprotein cholesterol (LDL\u2010C) and triglycerides were higher in the study group as compared to historical controls (95.60\u00a0\u00b1\u00a036.12 and 129.40\u00a0\u00b1\u00a064.62\u00a0mg\/dL <jats:italic>vs<\/jats:italic>. 80.10\u00a0\u00b1\u00a02.20 and 91.1\u00a0\u00b1\u00a029.85; <jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.05). Total cholesterol and high\u2010density lipoprotein cholesterol levels remained unaffected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children with <jats:styled-content style=\"fixed-case\">KD<\/jats:styled-content> (especially boys) had increased subcutaneous fat deposition in the suprailiac region and waist, during follow\u2010up. Serum <jats:styled-content style=\"fixed-case\">LDL<\/jats:styled-content>\u2010C and triglycerides were elevated. <jats:styled-content style=\"fixed-case\">KD<\/jats:styled-content> children may have a tendency to develop central obesity. Further studies, with longer follow\u2010up, would be necessary to show whether this has implications for development of coronary artery disease later in life.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.12296","type":"journal-article","created":{"date-parts":[[2014,2,12]],"date-time":"2014-02-12T11:01:17Z","timestamp":1392202877000},"page":"304-312","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Pattern of subcutaneous fat during follow\u2010up of a cohort of <scp>N<\/scp>orth <scp>I<\/scp>ndian children with <scp>K<\/scp>awasaki disease: a preliminary study"],"prefix":"10.1111","volume":"17","author":[{"given":"Renu","family":"Suthar","sequence":"first","affiliation":[{"name":"Pediatric Allergy Immunology Unit Department of Pediatrics Advanced Pediatrics Centre Post Graduate Institute of Medical Education and Research Chandigarh 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