{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T18:47:25Z","timestamp":1695494845912},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,3,6]],"date-time":"2014-03-06T00:00:00Z","timestamp":1394064000000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Polyarteritis nodosa in children is a rare necrotizing vasculitis affecting mainly small and medium\u2010size arteries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the different clinical patterns and laboratory profiles of polyarteritis nodosa patients in a tertiary care hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>This was a retrospective cohort study carried out in the Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh during the period January 2007 to December 2012. A total of 13 patients fulfilling the European League Against Rheumatism\/Paediatric Rheumatology International Trial Organization\/Paediatric Rheumatology European Society (<jats:styled-content style=\"fixed-case\">EULAR<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PRINTO<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PRES<\/jats:styled-content>) classification criteria were enrolled in this study. Data was collected via a predesigned questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Age range was 3\u201312\u00a0years, male\u00a0:\u00a0female ratio was 9\u00a0:\u00a04. The duration of symptoms was 2\u201316\u00a0weeks. All the children had fever, anorexia and generalized weakness. Subcutaneous nodules were present in 77% of cases followed by arthritis and rash (69%), muscle pain (54%) and abdominal pain (38%). Impaired peripheral pulses were present in 54%, ulceration and gangrene was present in 31% and auto\u2010amputation was present in 15% of cases. All the patients had high erythrocyte sedimentation rates followed by neutrophilic leukocytosis and thrombocytosis (85% and 62%). Skin biopsy was positive in 77% of cases and angiographic abnormalities were present in 23% of cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most clinical and laboratory profiles of polyarteritis nodosa in our center, such as age, sex, fever, rash, arthritis and abdominal pain, were mostly similar to other reports; however some late cases were found in this series with complications such as gangrene and auto\u2010amputation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.12319","type":"journal-article","created":{"date-parts":[[2014,3,6]],"date-time":"2014-03-06T06:58:40Z","timestamp":1394089120000},"page":"313-316","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical and laboratory profile of childhood polyarteritis nodosa in a Bangladeshi tertiary hospital"],"prefix":"10.1111","volume":"17","author":[{"given":"Manik K.","family":"Talukder","sequence":"first","affiliation":[{"name":"Department of Paediatrics Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad I.","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahana A.","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2009.07.004"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197601000-00001"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-81-2-195"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.116657"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.1997.tb03599.x"},{"key":"e_1_2_5_7_1","first-page":"459","article-title":"Polyarteritis nodosa \u2013 a few unusual findings","volume":"33","author":"Kumar L","year":"1996","journal-title":"Indian Pediatr"},{"key":"e_1_2_5_8_1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1542\/peds.60.2.227","article-title":"Polyarteritis nodosa in older children","volume":"60","author":"Blau EB","year":"1977","journal-title":"Pediatrics"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780220803"},{"key":"e_1_2_5_10_1","first-page":"911","article-title":"Childhood polyarteritis nodosa: a clinical diagnosis","volume":"43","author":"Mogale KD","year":"2006","journal-title":"Indian Pediatr"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM195304302481805"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780330805"},{"key":"e_1_2_5_13_1","first-page":"498","volume-title":"Textbook of Pediatric Rheumatology","author":"Michael JDillonMJ","year":"2011"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(80)90017-7"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.06.046"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-009-0059-4"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197908023010503"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1756-185X.12319","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.12319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T18:04:08Z","timestamp":1695492248000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1756-185X.12319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1111\/1756-185X.12319"],"URL":"https:\/\/doi.org\/10.1111\/1756-185x.12319","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"value":"1756-1841","type":"print"},{"value":"1756-185X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"2014-03-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}