{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T07:17:31Z","timestamp":1778915851751,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,5,5]],"date-time":"2014-05-05T00:00:00Z","timestamp":1399248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Faculty of Medicine, Songklanagarind Hospital"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the relationship of apolipoprotein B (Apo\u2010B) and arterial stiffness determined by brachial\u2010ankle pulse wave velocity (ba<jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>) in systemic lupus erythematosus (<jats:styled-content style=\"fixed-case\">SLE<\/jats:styled-content>) subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty\u2010seven Thai <jats:styled-content style=\"fixed-case\">SLE<\/jats:styled-content> subjects with inactive disease activity were studied. Fasting blood was collected for creatinine, glucose, lipid profiles, Apo\u2010B and Apo\u2010A1. Pearson correlation and stepwise\u2010linear regression were used for the analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of the subjects was 36.69\u00a0\u00b1\u00a010.85\u00a0years; 6.90% of them had stage 3 or more severe chronic kidney disease, 49.40% took anti\u2010hypertensive drugs and 4.60% had abnormal glucose metabolism. The mean value for ba<jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content> was 1332\u00a0\u00b1\u00a0274.12\u00a0cm\/s. Thirty\u2010six percent of the subjects had increased arterial stiffness with mean Apo\u2010B levels of 1.05\u00a0\u00b1\u00a00.31\u00a0g\/L compared to 0.94\u00a0\u00b1\u00a00.24 in normal arterial stiffness. There were correlations of ba<jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content> with age, systolic blood pressure (<jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>), diastolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> and creatinine clearance. Apo\u2010B tended to be associated with ba<jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content> (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.06) whereas low\u2010density lipoprotein cholesterol did not (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.2). By multiple regression analysis, systolic <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>, age and Apo\u2010B were the significant predictors of ba<jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Apo\u2010B was independently associated with arterial stiffness in <jats:styled-content style=\"fixed-case\">SLE<\/jats:styled-content> subjects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.12384","type":"journal-article","created":{"date-parts":[[2014,5,5]],"date-time":"2014-05-05T06:02:44Z","timestamp":1399269764000},"page":"447-451","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Apolipoprotein B as an independent predictor of arterial stiffness in systemic lupus erythematosus 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