{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T23:46:23Z","timestamp":1769730383106,"version":"3.49.0"},"reference-count":49,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,10,28]],"date-time":"2014-10-28T00:00:00Z","timestamp":1414454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Behcet's disease (<jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>) is a multisystem inflammatory disease characterized by recurrent aphthous ulcers, genital ulcers and uveitis. Demographic and clinical features of <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> are different in various countries. Due to these ethnic discrepancies, we decided to consider the clinical picture of <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> in the Azeri population of Iran and compare it with other ethnic groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional cohort study was carried out at the Connective Tissue Diseases Research Center of Tabriz University of Medical Sciences, Tabriz, Iran from 2006 to 2013. We considered the demographic and clinical findings in 166 patients with <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>. Disease activity was measured by the Iranian Behcet's Disease Dynamic Activity Measure (<jats:styled-content style=\"fixed-case\">IBDDAM<\/jats:styled-content>) and Total Inflammatory Activity Index (<jats:styled-content style=\"fixed-case\">TIAI<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The male\u2010to\u2010female ratio was 1.7\u00a0:\u00a01.0; the age of disease onset was 25.8\u00a0\u00b1\u00a08.9\u00a0years. Recurrent oral aphthous ulcers were the initial manifestations of <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> in 83.1% of patients. Panophthalmitis and panuveitis were the most common ophthalmic manifestations of disease. Blindness occurred in 7.1% of patients. This study showed no difference between the two genders in mean age of disease onset and clinical manifestations. However, <jats:styled-content style=\"fixed-case\">IBDDAM<\/jats:styled-content> in men was higher than women. Retinal vasculitis in men was more common than women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> in the Azeri population of Iran starts in the third decade and has a male predominance. The activity of the disease and retinal vasculitis in men is more predominant than women in Azerbaijan.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.12512","type":"journal-article","created":{"date-parts":[[2014,10,28]],"date-time":"2014-10-28T14:05:51Z","timestamp":1414505151000},"page":"1114-1119","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Demographic and clinical features of Behcet's disease in Azerbaijan"],"prefix":"10.1111","volume":"21","author":[{"given":"Alireza","family":"Khabbazi","sequence":"first","affiliation":[{"name":"Connective Tissue Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Noshad","sequence":"additional","affiliation":[{"name":"Connective Tissue Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farid K.","family":"Shayan","sequence":"additional","affiliation":[{"name":"Connective Tissue Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadise","family":"Kavandi","sequence":"additional","affiliation":[{"name":"Connective Tissue Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehrzad","family":"Hajialiloo","sequence":"additional","affiliation":[{"name":"Connective Tissue Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sousan","family":"Kolahi","sequence":"additional","affiliation":[{"name":"Connective Tissue Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)91268-5"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/38.12.1279"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.60.8.814"},{"key":"e_1_2_8_5_1","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1128\/iai.59.4.1434-1441.1991","article-title":"Association between the 65\u2010kilodalton heat shock protein. 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