{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:10:05Z","timestamp":1788869405569,"version":"build-2803163510"},"reference-count":9,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,1,3]],"date-time":"2015-01-03T00:00:00Z","timestamp":1420243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006765","name":"Chinese Medical Association","doi-asserted-by":"publisher","award":["12040670367"],"award-info":[{"award-number":["12040670367"]}],"id":[{"id":"10.13039\/501100006765","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2015,11]]},"abstract":"Abstract<\/jats:title>\n \n Aim<\/jats:title>\n \n To investigate the clinical and pathological characteristics of renal involvement in Behcet's disease (\n BD<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A retrospective analysis was carried out in\n BD<\/jats:styled-content>\n patients complicated with renal damage who were hospitalized in Peking Union Medical College Hospital from June 1998 to July 2012.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n There were 16\n BD<\/jats:styled-content>\n patients with renal involvement, accounted for 2.6% of all the 618 hospitalized\n BD<\/jats:styled-content>\n patients. The presentation of renal disease was chronic glomerulonephritis in six patients (including one with nephritic syndrome), renal tubular acidosis in one patient, renal artery stenosis in eight patients and renal vein thrombosis in one patient. Renal biopsy was performed in five patients, three of whom revealed to have minor glomerular lesions, mild mesangial proliferative glomerulonephritis and chronic tubular\u2010interstitial nephropathy, respectively. The other two patients underwent a second biopsy, the one with minor glomerular lesion in the first biopsy was transformed into grade\n III<\/jats:styled-content>\n immunoglobulin A (IgA) nephropathy on Lee's glomerular grading system 6\u00a0years later, and the other one who had IgA nephropathy of grade\n II<\/jats:styled-content>\n in the first biopsy was progressed to grade\n IV<\/jats:styled-content>\n 2\u00a0years later. Among the nine patients with renal vascular involvement, two underwent surgery, and several received anticoagulant therapy. During the follow\u2010up of 13 patients, the urine protein quantifications were reduced, and renal function remained relatively stable.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Renal damage is relatively uncommon in\n BD<\/jats:styled-content>\n patients. There are various clinical presentations of renal involvement in\n BD<\/jats:styled-content>\n . Routine screening with urinalysis, serum creatinine and imaging studies should be carried out for the early diagnosis of renal involvement in\n BD<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/1756-185x.12529","type":"journal-article","created":{"date-parts":[[2015,1,3]],"date-time":"2015-01-03T01:01:20Z","timestamp":1420246880000},"page":"892-897","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Renal involvement in Chinese patients with Behcet's disease: a report of 16 cases"],"prefix":"10.1111","volume":"18","author":[{"given":"Wenjie","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Peking Union Medical College Hospital Peking Union Medical College and Chinese Academy of Medical Sciences Key Laboratory of Rheumatology and Clinical Immunology Ministry of Education Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohua","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Nephrology Inner Mongolia Hospital of Traditional Chinese Medicine Hohhot China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Nephrology Peking Union Medical College Hospital Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Limeng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nephrology Peking Union Medical College Hospital Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinping","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Peking Union Medical College Hospital Peking Union Medical College and Chinese Academy of Medical Sciences Key Laboratory of Rheumatology and Clinical Immunology Ministry of Education Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengchun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Peking Union Medical College Hospital Peking Union Medical College and Chinese Academy of Medical Sciences Key Laboratory of Rheumatology and Clinical Immunology Ministry of Education Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,3]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"1078","article-title":"Criteria for diagnosis of Behcet's disease","volume":"335","author":"International Study Group for Behcet's Disease","year":"1990","journal-title":"Lancet"},{"key":"e_1_2_8_3_1","first-page":"244","article-title":"Clinical manifestations of Behcet's disease in Chinese patients","volume":"9","author":"Zhang ZL","year":"2006","journal-title":"Int J Rheum Dis"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/sarh.2002.31721"},{"issue":"42","key":"e_1_2_8_5_1","first-page":"S43","article-title":"Co\u2010morbidities in Beh\u00e7et's syndrome","volume":"24","author":"Karci C","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1081\/JDI-120028549"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2007.11.001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s100670200004"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-005-0621-y"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e318068d7c3"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1756-185X.12529","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.12529","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T20:12:07Z","timestamp":1696363927000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1756-185X.12529"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,3]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.1111\/1756-185X.12529"],"URL":"https:\/\/doi.org\/10.1111\/1756-185x.12529","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"value":"1756-1841","type":"print"},{"value":"1756-185X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,3]]},"assertion":[{"value":"2015-01-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}