{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T14:35:45Z","timestamp":1725978945543},"reference-count":14,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,3,4]],"date-time":"2016-03-04T00:00:00Z","timestamp":1457049600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To study the bone mineral density (BMD) profile in post\u2010menopausal women and to examine the role of various socio\u2010demographic, clinical, laboratory and radiological factors in predicting fracture risk in these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study recruited consenting postmenopausal women presenting with some form of pain complaints, such as joint pain, body ache, low back pain and so on. A structured questionnaire was used to collect socio\u2010demographic details. Height and weight were measured and BMI (body mass index) was calculated. Dual energy X\u2010ray absorptiometry was performed in three sites: lumbar spine (LS), femoral neck (FN) and trochanteric region (TR) to assess BMD. Serum levels of calcium, phosphorus and alkaline phosphatase were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 107 patients. Mean age was 59.70 \u00b1 9.02 years and mean age at menopause was 46.37 \u00b1 4.48 years. Fracture history was present in 25\/107 (23.36%). Mean BMI observed was 25.34 \u00b1 3.73. Women with fracture history had statistically significant differences in six factors, namely age, years since menopause, BMI and <jats:italic>T<\/jats:italic>\u2010score measurements at LS, FN and TR (<jats:italic>P<\/jats:italic> &lt; 0.05). Multivariate logistic regression analysis for these six variables revealed that no factor was independently associated with fracture risk, but those patients who had abnormal <jats:italic>T<\/jats:italic>\u2010scores in all three regions had significant history of fracture (<jats:italic>P<\/jats:italic> = 0.04).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Age, age since menopause, BMI, and BMD <jats:italic>T<\/jats:italic>\u2010score measurements at LS, FN and TR individually predict fracture risk, but none remain significant when all factors are considered together. Patients with abnormal BMD <jats:italic>T<\/jats:italic>\u2010scores in all three sites more often gave histories of fractures. Further studies are warranted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.12825","type":"journal-article","created":{"date-parts":[[2016,3,5]],"date-time":"2016-03-05T16:47:04Z","timestamp":1457196424000},"page":"1973-1977","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bone mineral density profile among post\u2010menopausal women in Manipur: a hospital\u2010based study"],"prefix":"10.1111","volume":"20","author":[{"given":"Romi Singh","family":"Nongmaithem","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Regional Institute of Medical Sciences Imphal Manipur India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minggam","family":"Pertin","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Regional Institute of Medical Sciences Imphal Manipur India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chongreilen","family":"Chiru","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Regional Institute of Medical Sciences Imphal Manipur India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yengkhom","family":"Jotin","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Regional Institute of Medical Sciences Imphal Manipur India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,3,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0b013e3181c617e6"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2000.15.4.721"},{"key":"e_1_2_8_4_1","first-page":"1547","volume-title":"Cecil Textbook of Medicine","author":"Finkelstein JS","year":"2004"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1876"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1359\/JBMR.041003"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115204"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2051"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-005-1863-y"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.22.2815"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001980170062"},{"key":"e_1_2_8_12_1","unstructured":"WHO(2015)Prevention and Management of Osteoporosis. Available from:http:\/\/whqlibdoc.who.int\/trs\/WHO_TRS_921.pdf[Cited 11 March 2015.]"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08761-5"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.312.7041.1254"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.12"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1756-185X.12825","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1756-185X.12825","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.12825","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:32:54Z","timestamp":1695573174000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1756-185X.12825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,4]]},"references-count":14,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1111\/1756-185X.12825"],"URL":"https:\/\/doi.org\/10.1111\/1756-185x.12825","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"value":"1756-1841","type":"print"},{"value":"1756-185X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,4]]},"assertion":[{"value":"2016-03-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}