{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T20:00:44Z","timestamp":1788206444173,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,2,23]],"date-time":"2016-02-23T00:00:00Z","timestamp":1456185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Chancellor for Research of Mashhad University of Medical Science, Mashhad, Iran","award":["900941"],"award-info":[{"award-number":["900941"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim and Objective<\/jats:title><jats:p>To evaluate the association between ultrasonographic findings of inflammation (effusion, synovitis) and clinical findings in patients with primary painful knee osteoarthritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This cross\u2010sectional study was performed on 142 patients with primary painful knee osteoarthritis (American College of Rheumatology criteria) in whom the visual analogue scale of pain was 30 or more. Clinical parameters were evaluated by a rheumatologist using Western Ontario and McMaster Universities Osteoarthritis Index (<jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content>) score while the ultrasonographic examination was performed by a musculoskeletal radiologist in our center. Knee joint synovitis and effusion were defined as synovial thickness \u2265 4 mm and depth of fluid in the suprapatellar recess \u2265 4 mm, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010eight (47.9%) patients demonstrated neither synovitis nor effusion, 37 (26.1%) had only effusion, 11 (7.7%) had only synovitis and 26 (18.3%) had both effusion and synovitis in the ultrasonographic examination. There was significant association between ultrasonographic knee arthritis (defined as presence of synovitis or effusion) and <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> pain sub\u2010score, <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> physical function sub\u2010score and <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> total score. No significant association was noted between sonographic signs of arthritis and <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> joint stiffness sub\u2010score. We also found significant correlation between ultrasonographic synovitis and <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> pain sub\u2010score (<jats:italic>P<\/jats:italic> &lt; 0.001), <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> physical function sub\u2010score (<jats:italic>P<\/jats:italic> &lt; 0.001) and total <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> score (<jats:italic>P<\/jats:italic> &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study revealed a positive correlation between ultrasonographic synovitis and total <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> score, <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> pain and physical function sub\u2010score. There was no association between sonographic signs of arthritis and <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> joint stiffness sub\u2010score.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.12834","type":"journal-article","created":{"date-parts":[[2016,2,26]],"date-time":"2016-02-26T02:49:19Z","timestamp":1456454959000},"page":"561-566","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Association between clinical and sonographic synovitis in patients with painful knee osteoarthritis"],"prefix":"10.1111","volume":"20","author":[{"given":"Bita","family":"Abbasi","sequence":"first","affiliation":[{"name":"Radiology Department Ghaem Hospital Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Pezeshki\u2010Rad","sequence":"additional","affiliation":[{"name":"Vascular and Interventional 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