{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T07:42:24Z","timestamp":1696059744978},"reference-count":13,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,8,12]],"date-time":"2016-08-12T00:00:00Z","timestamp":1470960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Multiple myeloma can rarely mimic seronegative rheumatoid arthritis (<jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>). We report a 55\u2010year\u2010old woman who presented with longstanding deforming polyarthritis with extensive subcutaneous nodules, tenosynovitis, anti\u2010cyclic citrullinated peptide positivity and mononeuritis multiplex. Even though the clinical picture was consistent with seropositive <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>, the absence of bone erosion or joint space narrowing on hand and knee radiographs led us to question the diagnosis of <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>. Further investigation revealed a diagnosis of multiple myeloma with cutaneous amyloid deposits, based on serum immunofixation, bone marrow aspiration and biopsy of a subcutaneous nodule. The only clue to suspect myeloma from the basic investigations and clinical examination was mild hypercalcemia. This case serves to reiterate the need to maintain a heightened suspicion for other diagnoses even when <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> appears most likely.<\/jats:p>","DOI":"10.1111\/1756-185x.12935","type":"journal-article","created":{"date-parts":[[2016,8,12]],"date-time":"2016-08-12T10:26:40Z","timestamp":1470997600000},"page":"1297-1302","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Multiple myeloma masquerading as severe seropositive rheumatoid arthritis with subcutaneous nodules and mononeuritis multiplex"],"prefix":"10.1111","volume":"20","author":[{"given":"Sukesh","family":"Edavalath","sequence":"first","affiliation":[{"name":"Department of Clinical Immunology Sanjay Gandhi Post Graduate Institute of Medical Sciences Lucknow Uttar Pradesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhra 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