{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:45:30Z","timestamp":1764783930625,"version":"build-2065373602"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T00:00:00Z","timestamp":1487203200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008968","name":"National Research Council Sri Lanka","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study was done to determine the association between chronic low back pain and vertebral fractures, intervertebral disc space (<jats:styled-content style=\"fixed-case\">IDS<\/jats:styled-content>) narrowing, vertebral osteophytes and spondylolisthesis among adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This case control study was done in Sri Lanka. Cases were patients with low back pain and controls were without low back pain. Postero\u2010anterior and lateral radiographs of lumbar sacral spine of both groups were studied. To detect vertebral fractures in fourth and fifth lumbar vertebrae, anterior and posterior heights of vertebrae were measured using a Vernier caliper and antero\u2010posterior ratio (A\/P) was calculated. Having an A\/P ratio value of &lt; 0.89 was considered as a vertebral fracture. Presence of disc space narrowing, vertebral osteophytes and spondylolisthesis was assessed by two radiologists working independently. Bivariate and logistic regression analysis was done to find associations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 140 cases and 140 controls. Mean (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) age for cases was 51.6 (17) years. Mean (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) age for controls was 50 (15) years. Females made up 62% of cases and controls. Fifth lumbar vertebral fracture (odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>] = 10.2;<jats:italic>P<\/jats:italic>= 0.001), fourth lumbar vertebral fracture (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>= 2.5;<jats:italic>P<\/jats:italic>= 0.017) and<jats:styled-content style=\"fixed-case\">IDS<\/jats:styled-content>narrowing (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>= 4.15,<jats:italic>P<\/jats:italic>= 0.009) had a significant association with low back pain and vertebral osteophytes and spondylolisthesis did not have a significant association with low back pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Only vertebral fractures and<jats:styled-content style=\"fixed-case\">IDS<\/jats:styled-content>narrowing had a significant association with chronic low back pain.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13026","type":"journal-article","created":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T08:33:16Z","timestamp":1487233996000},"page":"602-610","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Chronic low back pain and its association with lumbar vertebrae and intervertebral disc changes in adults. 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