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There are also regional and ethnic variations in the incidence, the genetics of which is being studied. The recommended best therapy for the acute attacks and long term prophylaxis has improved remarkably in the recent years. However, patients are often treated inadequately and risk factors for their disease are not well explored in daily practice. Although well designed long term studies of current and newer treatment are welcomed, educating doctors especially the primary care physicians who manage majority of gout cases, in optimizing the currently available management options would improve the present care.<\/jats:p>","DOI":"10.1111\/1756-185x.13103","type":"journal-article","created":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T03:02:39Z","timestamp":1496718159000},"page":"407-416","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Gout: an Asia\u2010Pacific update"],"prefix":"10.1111","volume":"20","author":[{"given":"Binoy J.","family":"Paul","sequence":"first","affiliation":[{"name":"Department of General Medicine KMCT Medical College Calicut Kerala India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8762-2774","authenticated-orcid":false,"given":"Reeta","family":"James","sequence":"additional","affiliation":[{"name":"Department of General Medicine KMCT Medical College Calicut Kerala India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0973-3698(10)60205-1"},{"key":"e_1_2_8_3_1","first-page":"687","article-title":"Hippocrates and rheumatology","volume":"22","author":"Pasero G","year":"2004","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0973-3698(09)60111-4"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-54-3-452"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.5152\/eurjrheumatol.2014.021"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2014-205877"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar3816"},{"key":"e_1_2_8_9_1","first-page":"61","article-title":"Clinical spectrum of gout in South India","volume":"10","author":"Porkodi R","year":"2002","journal-title":"J Indian Rheumatol Assoc"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-009-1362-1"},{"key":"e_1_2_8_11_1","first-page":"1893","volume-title":"Rheumatology","author":"Poor G","year":"2003"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2006.03.008"},{"volume-title":"Epidemiology of Rheumatic Diseases","year":"2001","author":"Silman A","key":"e_1_2_8_13_1"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/23.4.276"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/33.10.932"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24938"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(81)90101-3"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq412"},{"issue":"7","key":"e_1_2_8_19_1","first-page":"1364","article-title":"High prevalence of gout and related risk factors in Taiwan's Aborigines","volume":"24","author":"Chang S","year":"1997","journal-title":"J Rheumatol"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/scientificamerican0791-88"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.2174\/157339711795305022"},{"issue":"5","key":"e_1_2_8_22_1","first-page":"965","article-title":"Rheumatic disease in an Australian Aboriginal community in North Queensland, Australia. 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