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Existing RA recommendations, in relation to the use of bDMARDs and tsDMARD, were identified and evaluated by the AGREE II instrument prior to their use as a \u2018guide\u2019 for developing this TRA recommendation. An additional literature search was performed in order to answer specific clinical questions that could not be found in existing guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Result<\/jats:title><jats:p>Thirteen recommendations were developed. They covered the use of RA classification criteria, the aim of RA treatment, when to initiate bDMARDs\/tsDMARD or taper or switch them to other medications, as well as monitoring these drugs during their use. In addition, specific issues including their use and vaccination, malignancies, pregnancy and lactation, and perioperative period also were addressed. Public hearings were performed at the annual meeting of the TRA and of the Royal College of Physicians of Thailand. The recommendations were distributed to other professional associations related to RA management, as well as government sectors associated with the reimbursement policy, prior to development of the final version.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These recommendations will help Thai rheumatologists prescribe bDMARDs and tsDMARD more appropriately when treating RA patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13130","type":"journal-article","created":{"date-parts":[[2017,7,21]],"date-time":"2017-07-21T08:24:14Z","timestamp":1500625454000},"page":"1166-1184","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["2016 updated Thai Rheumatism Association Recommendations for the use of biologic and targeted synthetic disease\u2010modifying anti\u2010rheumatic drugs in patients with rheumatoid 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