{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:39:13Z","timestamp":1780472353792,"version":"3.54.1"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,8,7]],"date-time":"2017-08-07T00:00:00Z","timestamp":1502064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Idiopathic inflammatory myopathies (<jats:styled-content style=\"fixed-case\">IIM<\/jats:styled-content>) comprise a group of rare and heterogeneous diseases difficult to diagnose and follow up. Precise measures for assessing disease activity are not available at the moment. Our objective was to evaluate the usefulness of ultrasonography (<jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>) as a monitoring tool in <jats:styled-content style=\"fixed-case\">IIM<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>The study evaluated <jats:styled-content style=\"fixed-case\">IIM<\/jats:styled-content> patients diagnosed and followed up from 2005 to 2015 in our department. Fifteen patients with a mean age of 52.2\u00a0\u00b1\u00a022.09\u00a0years and mean disease duration of 4.6\u00a0\u00b1\u00a03.20\u00a0years were included. Physical examination including muscle strength tests, laboratorial analysis and a selective muscle <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> assessment were performed for each patient at a scheduled visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nine of the 15 patients were in clinical remission and <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> assessment revealed a preserved muscle pattern. Symmetrical proximal muscle atrophy was found on <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> in one patient with longstanding polymyositis (<jats:styled-content style=\"fixed-case\">PM<\/jats:styled-content>) with proximal weakness. Inflammation and focal or generalized muscle edema were present on <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> in the remaining five patients with muscular weakness suggesting active disease. One of these patients in acute flare presented with atrophy changes in addition to edema. Early untreated myositis presented in one patient with moderate power Doppler (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>) signal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>As far as muscle <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> assessment is concerned, a single specific pattern was not observed in our study. A mixture of muscle edema and atrophy was detected depending on disease activity and duration. <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> findings seem to correlate well with disease activity, suggested by clinical data, and may be a useful tool to complement patient evaluation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13150","type":"journal-article","created":{"date-parts":[[2017,8,7]],"date-time":"2017-08-07T05:52:37Z","timestamp":1502085157000},"page":"233-239","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Relevance of ultrasonography in assessing disease activity in patients with idiopathic inflammatory myopathies"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9929-0604","authenticated-orcid":false,"given":"Joana","family":"Sousa Neves","sequence":"first","affiliation":[{"name":"Department of Rheumatology Hospital Conde de Bertiandos 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