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Blood samples were collected 30 and 5 min before, immediately after and 1, 2 and 24 h after the session. We used analysis of variance for repeated\u2010measures with Bonferroni adjustments to assess differences between groups over time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In both groups we found significant changes in interleukin (<jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>)\u20101 beta (<jats:italic>P<\/jats:italic> = 0.045), <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20101 receptor antagonist (<jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20101ra) (<jats:italic>P<\/jats:italic> &lt; 0.001), <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201010 (<jats:italic>P<\/jats:italic> = 0.004), <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20106 (<jats:italic>P<\/jats:italic> &lt; 0.001) and cartilage oligomeric matrix protein (<jats:styled-content style=\"fixed-case\">COMP<\/jats:styled-content>) <jats:italic>P<\/jats:italic> &lt; 0.001) in response to exercise, but no changes in tumor necrosis factor\u2013alpha and C\u2010reactive protein levels. We found no differences in the responses of the two groups to the session, except for <jats:styled-content style=\"fixed-case\">COMP<\/jats:styled-content> levels, which are more sensitive to exercise and rest effects in <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Women with and without <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> have similar changes in response to a <jats:styled-content style=\"fixed-case\">RE<\/jats:styled-content> session in levels of inflammation biomarkers, but not of cartilage breakdown. <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201010 and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20101ra increased after the <jats:styled-content style=\"fixed-case\">RE<\/jats:styled-content> session, indicating that <jats:styled-content style=\"fixed-case\">RE<\/jats:styled-content> may have an acute anti\u2010inflammatory effect. Additional studies are necessary to clarify if repeated <jats:styled-content style=\"fixed-case\">RE<\/jats:styled-content> sessions can have long\u2010term anti\u2010inflammatory effects and the possible clinical repercussions of this cartilage breakdown characteristic in response to exercise in <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13204","type":"journal-article","created":{"date-parts":[[2017,11,3]],"date-time":"2017-11-03T15:30:33Z","timestamp":1509723033000},"page":"1704-1713","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Acute effect of a resistance exercise session on markers of cartilage breakdown and inflammation in women with rheumatoid arthritis"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1505-877X","authenticated-orcid":false,"given":"Ana Carolina","family":"Pereira Nunes 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